McDonnell P J, Moreira H, Garbus J, Clapham T N, D'Arcy J, Munnerlyn C R
Doheny Eye Institute, Department of Ophthalmology, University of Southern California School of Medicine, Los Angeles 90033.
Arch Ophthalmol. 1991 May;109(5):710-3. doi: 10.1001/archopht.1991.01080050126042.
Excimer laser photorefractive keratectomy, developed to perform radially symmetric ablations to correct myopic or hyperopic refractive errors, was used to create toric ablations designed to correct cylindrical errors. An expanding slit was created, with no refractive change intended parallel to the slit opening, and central flattening was induced in the meridian in which the slit was expanded. In polymethyl methacrylate blocks, the induced cylinder (as measured with a lensometer) agreed closely (r2 = .99) with intended change, and in plastic corneas, induction of the cylinder could be demonstrated with computer-assisted topographic analysis. Adult pigmented rabbits underwent induction of toric ablations in two-diopter increments; measured keratometric change correlated with desired change (r2 = .87 at 3 weeks; r2 = .89 at 12 weeks). Toric ablations with the excimer laser appear to represent a promising strategy for the correction of cylindrical errors that do not rely on creation of deep corneal incisions, excisions, or compression sutures.
准分子激光屈光性角膜切削术最初用于进行径向对称消融以矫正近视或远视屈光不正，后来被用于创建旨在矫正柱面像差的环曲面消融。创建一个扩张的裂隙，裂隙开口方向不产生屈光变化，并在裂隙扩张的子午线方向诱导中央变平。在聚甲基丙烯酸甲酯块中，诱导的柱面（用焦度计测量）与预期变化密切相关（r2 = 0.99），在塑料角膜中，通过计算机辅助地形图分析可以证明柱面的诱导。成年有色家兔以两屈光度的增量进行环曲面消融诱导；测量的角膜曲率变化与预期变化相关（3周时r2 = 0.87；12周时r2 = 0.89）。准分子激光环曲面消融似乎是一种有前景的矫正柱面像差的策略，该策略不依赖于制作深层角膜切口、切除术或加压缝线。
