Zhang Y, Joines W T, Oleson J R
Department of Electrical Engineering, Duke University, Durham, NC 27706.
IEEE Trans Biomed Eng. 1991 Jan;38(1):92-7. doi: 10.1109/10.68215.
In this paper, we investigate an array of six interstitial microwave antennas used for hyperthermia cancer treatment. The purpose is to generate both uniform and controlled nonuniform heating patterns in biological tissue by phase modulating the signals applied to each antenna. The array consists of six antennas positioned on the corners of a hexagon. The distance between two diagonal antennas is 4 cm. The distributions of absorbed power per unit mass within the array are computed, and then converted into temperature distributions through a thermal conduction simulation. The SAR and temperature patterns are presented in both the lateral plane (perpendicular to the antennas) and the axial plane (parallel with the antennas). By proper phase modulation of microwave signals applied to each antenna, a uniform heating pattern can be produced within the entire array volume. Also, a peripheral heating pattern may be generated around the array; again, by using the proper phase modulation. The modulation schemes for generating both types of heating patterns are discussed.
在本文中，我们研究了用于热疗癌症治疗的六个间质微波天线阵列。目的是通过对施加到每个天线的信号进行相位调制，在生物组织中产生均匀且可控的非均匀加热模式。该阵列由位于六边形角上的六个天线组成。两个对角天线之间的距离为4厘米。计算阵列内每单位质量吸收功率的分布，然后通过热传导模拟将其转换为温度分布。在横向平面（垂直于天线）和轴向平面（平行于天线）中呈现比吸收率（SAR）和温度模式。通过对施加到每个天线的微波信号进行适当的相位调制，可以在整个阵列体积内产生均匀的加热模式。同样，通过使用适当的相位调制，也可以在阵列周围产生周边加热模式。讨论了产生这两种加热模式的调制方案。
