Cherry P C, Iskander M F
Department of Electrical Engineering, University of Utah, Salt Lake City 84112.
IEEE Trans Biomed Eng. 1993 Aug;40(8):771-9. doi: 10.1109/10.238461.
In this paper, the heating (temperature) distribution patterns of an array of uniformly and step-insulated interstitial antennas located in inhomogeneous tissue and cancerous regions of the human body are calculated. Specifically, the bioheat equation, which takes into account various heat exchange mechanisms such as blood flow rate, heat conduction, and metabolic heat generation, was solved using the finite difference method, while the electromagnetic power absorbed (SAR) in the tissue region heated using an array of interstitial antennas was determined using the finite-difference time-domain (FDTD) method. Numerical results showing the validation of the developed computer program are presented, and the effect of varying parameters such as the blood flow rate on the resulting heating rate and patterns are examined. Possible clinical implementation of the developed temperature distribution-EM power deposition pattern computer code in treatment planning is described.
本文计算了位于人体非均匀组织和癌性区域的一组均匀且阶梯绝缘的组织间天线的加热（温度）分布模式。具体而言，使用有限差分法求解了考虑诸如血流速率、热传导和代谢热生成等各种热交换机制的生物热方程，同时使用时域有限差分（FDTD）方法确定了使用一组组织间天线加热的组织区域中吸收的电磁功率（比吸收率）。给出了显示所开发计算机程序有效性的数值结果，并研究了诸如血流速率等变化参数对所得加热速率和模式的影响。描述了所开发的温度分布 - 电磁功率沉积模式计算机代码在治疗计划中可能的临床应用。
