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植入前小鼠胚胎中促黄体激素（LH）和人绒毛膜促性腺激素（hCG）结合“位点”的免疫细胞化学定位

Immunocytochemical localization of binding 'sites' for LH and hCG in preimplantation mouse embryos.

作者信息

SenGupta J, Gupta P D, Manchanda S K, Talwar G P

出版信息

J Reprod Fertil. 1978 Jan;52(1):163-5. doi: 10.1530/jrf.0.0520163.

DOI:10.1530/jrf.0.0520163
PMID:202706
Abstract

By using an immunoperoxidase antibody method, mouse blastocysts were found to bind specifically hCG and ovine LH but not FSH or the beta unit of hCG. Brown peroxidase reaction products were present in the morula and increased with the formation of the blastocoele. The LH/hCG binding 'sites' may be related to the initiation of steroidogenesis in the embryo.

摘要

通过使用免疫过氧化物酶抗体法，发现小鼠囊胚能特异性结合人绒毛膜促性腺激素（hCG）和绵羊促黄体生成素（LH），但不结合促卵泡生成素（FSH）或hCG的β亚基。桑椹胚中存在棕色过氧化物酶反应产物，且随着囊胚腔的形成而增加。LH/hCG结合“位点”可能与胚胎中类固醇生成的起始有关。

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