Dotzauer H, Wall H
Zentralinstitut für Arbeitsmedizin Berlin.
Z Gesamte Hyg. 1991 Jan;37(1):31-4.
In order to investigate the influence of hygienic measures (mobilisation yield of lead in urine by CaEDTA, part-time work) on psychological performance 23 lead exposed workers have been psychodiagnostically investigated twice along with biological monitoring (blood lead level, erythrocyte protoporphyrine). In the pre-post comparison 4 of the 6 performance ranges measured showed distinct performance improvements, which could be shown to be statistically significant for group comparisons and in most individual cases. Parameters sensitive to changes were in the motor-sensory choice reaction, concentration and memory while subjective estimations of well-being exhibited no changes. Also after discussing methodological questions (influence of age, test repetition) the changes are interpreted in the direction of a possible reversibility of neurotoxic effects as a consequence of hygienic interventions.
为了研究卫生措施（CaEDTA动员尿铅排出量、兼职工作）对心理表现的影响，对23名铅暴露工人进行了两次心理诊断调查，并同时进行了生物监测（血铅水平、红细胞原卟啉）。在前后比较中，所测量的6项表现范围中有4项显示出明显的表现改善，在组间比较以及大多数个体案例中，这些改善具有统计学意义。对变化敏感的参数包括运动感觉选择反应、注意力和记忆力，而主观幸福感评估未显示出变化。在讨论了方法学问题（年龄的影响、测试重复）之后，这些变化被解释为卫生干预可能导致神经毒性效应可逆的方向。
