Alvisi V, Degli Uberti E, Tralli G
Minerva Med. 1977 Dec 22;68(62):4183-91.
It has recently been noted that peripheral nerve fibres are involved in the course of chronic liver disease. The existence of hepatic polyneuropathy is still a matter of debate. A series of 29 subjects (not including diabetics or alcoholics) were examined clinically and electromyographically. Signs of distal lower extremity polyneuritis (paresthesia, hypoesthesia and osteotendinous hypo-areflexia) were noted in 31%. Latent neuropathy was observed in the form of slow maximum and minimum motor conduction rates in clinically unimpaired nerves. Electromyographical alterations were more evident in subjects with frankly chronic as opposed to barely chronic liver disease.
最近有研究指出,外周神经纤维参与了慢性肝病的病程。肝性多发性神经病的存在仍存在争议。对29名受试者(不包括糖尿病患者或酗酒者)进行了临床和肌电图检查。31%的受试者出现了下肢远端多发性神经炎的症状(感觉异常、感觉减退和肌腱反射减退)。在临床未受损的神经中,以运动传导速度的最大和最小值缓慢的形式观察到潜在的神经病变。与轻度慢性肝病患者相比,明显慢性肝病患者的肌电图改变更为明显。