Room 271 College of Health Building, University of Oklahoma Health Sciences Center, P.O. Box 26901, Oklahoma City, OK, 73190, USA.
Platelets. 1997;8(2-3):93-104. doi: 10.1080/09537109709169324.
A number of hematopoietic growth factors and other cytokines are capable of altering platelet production and function. Enhancement of these processes may be exploited to ameliorate bleeding propensity in thrombocytopenic patients. Under certain circumstances, cytokines may have adverse effects on the hemostatic system, potentially involved in thrombogenesis and atherogenesis. Inhibition of those cytokines may prove to be a useful experimental approach to investigate their potential pathophysiologic role.
许多造血生长因子和其他细胞因子能够改变血小板的产生和功能。增强这些过程可能被用来改善血小板减少症患者的出血倾向。在某些情况下，细胞因子可能对止血系统产生不良影响，潜在地参与血栓形成和动脉粥样硬化形成。抑制这些细胞因子可能被证明是一种有用的实验方法，以研究它们潜在的病理生理作用。
