Sundblad Britt-Marie, Larsson Kjell, Nathell Lennart
Lung and Allergy Research, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Clin Respir J. 2008 Jan;2(1):11-6. doi: 10.1111/j.1752-699X.2007.00020.x.
Early identification of patients with chronic obstructive pulmonary disease (COPD) in the health care system followed by successful smoking cessation may prevent rapid lung function deterioration, development of severe COPD and respiratory failure.
The aim of this study was to determine the frequency of under-diagnosed chronic obstructive lung diseases among current smokers.
The under-diagnosis of COPD among smokers was determined in subjects who participated in a screening procedure aimed at recruiting COPD patients for a smoking cessation programme. In order to identify current smokers, a questionnaire was sent out to persons who had been on sick leave for various reasons certified by a physician for more than 2 weeks. Subjects who stated that they currently smoked more than eight cigarettes per day were invited to perform a lung function test.
A total of 3887 subjects performed spirometry, i.e. forced expiratory volume in 1 s and forced expirations, and among these, 674 (17.3%) had COPD according to the European Respiratory Society (ERS) consensus guidelines. Of those, 103 (17.3%) had physician-diagnosed COPD. Productive cough was reported by 16.6% of the COPD subjects. Despite the fact that smokers were on sick leave certified by a physician, more than 80% of those with COPD had no previous diagnosis. As the COPD diagnosis cannot be based on reported symptoms, a spirometry on persons at risk must be performed.
The awareness of COPD among primary care physicians has to increase and smokers above the age of 40, with and without respiratory symptoms, have to undergo spirometry if it is regarded important to establish the COPD diagnosis at an early stage.
在医疗保健系统中早期识别慢性阻塞性肺疾病(COPD)患者并成功戒烟,可能会防止肺功能迅速恶化、严重COPD的发展以及呼吸衰竭。
本研究的目的是确定当前吸烟者中慢性阻塞性肺疾病诊断不足的频率。
在参与一项旨在为戒烟计划招募COPD患者的筛查程序的受试者中,确定吸烟者中COPD的诊断不足情况。为了识别当前吸烟者,向因各种原因经医生证明病假超过2周的人员发送了一份问卷。那些表示目前每天吸烟超过8支的受试者被邀请进行肺功能测试。
共有3887名受试者进行了肺活量测定,即1秒用力呼气量和用力呼气量,其中674名(17.3%)根据欧洲呼吸学会(ERS)共识指南患有COPD。其中,103名(17.3%)有医生诊断的COPD。16.6%的COPD受试者报告有咳痰。尽管吸烟者有医生开具的病假证明,但超过80%的COPD患者以前未被诊断。由于COPD的诊断不能基于报告的症状,因此必须对有风险的人员进行肺活量测定。
初级保健医生对COPD的认识必须提高,如果认为早期诊断COPD很重要,40岁以上有或无呼吸道症状的吸烟者必须接受肺活量测定。