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生命最后两年的慢性阻塞性肺疾病(COPD)——一项对死者的回顾性研究

Chronic obstructive pulmonary disease (COPD) during the two last years of life--a retrospective study of decedents.

作者信息

Sundblad Britt-Marie, Jansson Sven-Arne, Nyström Lennarth, Arvidsson Peter, Lundbäck Bo, Larsson Kjell

机构信息

Lung and Allergy Research, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.

出版信息

PLoS One. 2013 Dec 19;8(12):e84110. doi: 10.1371/journal.pone.0084110. eCollection 2013.

Abstract

BACKGROUND

Little is known about the management of patients suffering from chronic obstructive pulmonary disease (COPD) during the last years of life. The aim of the study was to describe how management of COPD is performed in Sweden during the last two years of life.

METHODS

From the nationwide Cause of Death register all individuals with COPD as the underlying cause of death during two years were identified in one sparsely and one densely populated area of Sweden. Data were collected from medical records using a pre-defined protocol, especially developed for this purpose.

RESULTS

Of 822 individuals with COPD as underlying cause of death, medical records from 729 were available. The COPD diagnosis was based on lung function measurements in approximately half of the patients and median age at COPD diagnosis was 74 years (range 34-95). Women died at younger age, median 78 years (range 52-96) than did men (80 years (51-99)). The median survival time from diagnosis to death was 6 years in men and women in both areas. Among women and men 8.3% and 4.3% were never smokers, respectively. The structure of COPD management differed between the two areas, with utilization of physiotherapists, dieticians and working therapists being more used in the northern area, likely because of differences in accessibility to care institutions.

CONCLUSIONS

In Sweden COPD is mostly diagnosed late in life and often not verified by lung function measurements. Opposite to the general population, women with COPD die at a lower age than men.

摘要

背景

对于慢性阻塞性肺疾病(COPD)患者在生命最后几年的管理知之甚少。本研究的目的是描述瑞典在生命最后两年中对COPD的管理方式。

方法

从全国死因登记册中,在瑞典一个人口稀少和一个人口密集的地区,确定了所有在两年内以COPD为根本死因的个体。使用专门为此目的制定的预定义方案从医疗记录中收集数据。

结果

在822例以COPD为根本死因的个体中,有729例的医疗记录可用。约一半患者的COPD诊断基于肺功能测量,COPD诊断时的中位年龄为74岁(范围34 - 95岁)。女性死亡年龄比男性小,女性中位年龄为78岁(范围52 - 96岁),男性为80岁(51 - 99岁)。两个地区男性和女性从诊断到死亡的中位生存时间均为6年。女性和男性中分别有8.3%和4.3%从不吸烟。两个地区的COPD管理结构有所不同,北部地区更多地利用物理治疗师、营养师和职业治疗师,这可能是由于获得医疗机构的机会不同所致。

结论

在瑞典,COPD大多在生命后期被诊断出来,且往往未通过肺功能测量来证实。与普通人群相反,患有COPD的女性比男性死亡年龄更低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7760/3868592/133034285a15/pone.0084110.g001.jpg

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