Manara Renzo, Calderone Milena, Severino Maria Savina, Citton Valentina, Toldo Irene, Laverda Anna Maria, Sartori Stefano
Neuroradiologic Unit, University Hospital of Padua, Padua, Italy.
J Child Neurol. 2010 Aug;25(8):1024-8. doi: 10.1177/0883073809355822. Epub 2010 Mar 18.
Fibrocartilaginous embolization is a rare cause of ischemic myelopathy caused by embolization of intersomatic disk nucleus pulposus into spinal vasculature during Valsalva-like maneuvers. Diagnostic criteria are based on patient's clinical history, magnetic resonance evidence of T2-hyperintense spinal cord lesion, and exclusion of other causes of ischemic myelopathy. These criteria do not take into account the development of magnetic resonance techniques able to enhance signal abnormalities within the neighboring intersomatic disc or vertebral body and to early characterize central nervous system lesions according to the presence of cytotoxic edema. We present 2 pediatric cases of progressive paraplegia attributed to fibrocartilaginous embolization in which short-tau inversion recovery and diffusion-weighted imaging sequences played a pivotal role showing the ischemic nature of spinal cord lesions. Due to its specificity, diffusion-weighted imaging should be included in the magnetic resonance criteria of fibrocartilaginous embolization and in standard magnetic resonance analysis when dealing with acute transverse myelopathy.
纤维软骨栓塞是一种罕见的缺血性脊髓病病因,由类似瓦尔萨尔瓦动作时椎间盘髓核栓塞至脊髓血管所致。诊断标准基于患者的临床病史、T2加权像上脊髓病变呈高信号的磁共振成像证据以及排除缺血性脊髓病的其他病因。这些标准未考虑到磁共振技术的发展,该技术能够增强相邻椎间盘或椎体内部的信号异常,并根据细胞毒性水肿的存在对中枢神经系统病变进行早期特征性诊断。我们报告2例因纤维软骨栓塞导致进行性截瘫的儿科病例,其中短反转时间反转恢复序列和扩散加权成像序列发挥了关键作用,显示了脊髓病变的缺血性质。由于其特异性,扩散加权成像应纳入纤维软骨栓塞的磁共振诊断标准以及处理急性横贯性脊髓病时的标准磁共振分析中。