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一名青少年男性因临床疑似纤维软骨栓塞导致的缺血性脊髓病的急性表现及长期康复随访:病例报告与文献复习

Acute Presentation and Long-Term Rehabilitation Follow-Up of Ischemic Myelopathy Due to Clinically Suspected Fibrocartilaginous Embolism in an Adolescent Male: A Case Report and Review.

作者信息

Berla Einat, Kerzhner Oleg, Caspi Tomm, Shaklai Sharon, Michaeli Dianne

机构信息

Israel Defense Forces Medical Corps, Ramat Gan 02149, Israel.

Loewenstein Rehabilitation Medical Center, Ra'anana 43100, Israel.

出版信息

Neurol Int. 2023 Oct 19;15(4):1273-1289. doi: 10.3390/neurolint15040080.

Abstract

Ischemic myelopathy is uncommon in the pediatric population, with fibrocartilaginous embolism (FCE) being one of its rarest causes. We present the case of an otherwise healthy 17-year-old student who experienced sudden onset of severe low-back pain amidst intensive physical training, which rapidly deteriorated to complete sensory-motor paralysis of his lower limbs. He was treated with IV Methylprednisolone and anticoagulation after the initial work-up suggested spinal cord infarction. After eight days, sufficient clinical-radiological correlation was achieved to support FCE diagnosis as the most likely cause of infarction. He subsequently received inpatient rehabilitation treatment for four months, after which he was followed as an outpatient for a total period of 16 months. While significant neurological and functional gains were achieved during this period, he also experienced some worsening. This case highlights the importance both of performing a thorough assessment and being familiar with FCE as a possible differential diagnosis of spinal cord infarction in children, to facilitate its timely identification and proper acute and long-term management. This case report was prepared following CARE guidelines after obtaining the patient's written informed consent.

摘要

缺血性脊髓病在儿科人群中并不常见,纤维软骨栓塞(FCE)是其最罕见的病因之一。我们报告了一例原本健康的17岁学生病例,该学生在高强度体育训练期间突然出现严重的下背部疼痛,并迅速恶化为下肢完全性感觉运动麻痹。在初步检查提示脊髓梗死之后,他接受了静脉注射甲泼尼龙和抗凝治疗。八天后,通过充分的临床与影像学关联分析,支持将FCE诊断为梗死最可能的病因。随后,他接受了四个月的住院康复治疗,之后作为门诊患者随访了16个月。在此期间,虽然他在神经功能和功能恢复方面取得了显著进展,但也出现了一些病情恶化的情况。该病例强调了进行全面评估以及熟悉FCE作为儿童脊髓梗死可能鉴别诊断的重要性,以便及时识别并进行适当的急性和长期管理。本病例报告是在获得患者书面知情同意后按照CARE指南编写的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/62a1/10594434/7f381721f189/neurolint-15-00080-g001.jpg

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