Guglielmi F W, Contento F, Laddaga L, Panella C, Francavilla A
Department of Gastroenterology, University of Bari, Italy.
Hepatology. 1991 May;13(5):892-5.
Bioelectric impedance analysis is a new, convenient and portable method used to estimate total body water and to assess body composition in healthy people. We used the tetrapolar bioelectrical impedance analysis method in 58 cirrhotic patients to assess its clinical applicability. Whole-body resistance, reactance and impedance were measured and compared with those of 30 healthy volunteers matched for age and sex. The resistance and impedance values of ascitic cirrhotic patients (resistance = 461 +/- 80 omega; impedance = 462 +/- 80 omega) and nonascitic cirrhotic patients (resistance = 487 +/- 96 omega; impedance = 489 +/- 97 omega) were comparable with the resistance (488 +/- 44 omega) and impedance (491 +/- 44 omega) of controls. However, a significant (p less than 0.05) reduction in whole body reactance was found in patients with ascites and in those without ascites (34 +/- 9 omega vs. 47 +/- 12 omega) as compared with healthy subjects (56 +/- 7 omega). In 10 ascitic patients total body water was determined both before and after paracentesis; the volume of intraperitoneal fluid removed (7.9 +/- 3.8 L) could not be fully accounted for but only detected as an average volume of 1.9 +/- 1.0 L independently of the initial volume of the ascites. Our data clearly demonstrate that tetrapolar bioelectric impedance analysis is not adequate for measuring variations of "compartmentalized" fluid in the abdomen.
生物电阻抗分析是一种新型、便捷且便携的方法，用于估计健康人群的全身水含量并评估身体成分。我们对58例肝硬化患者采用四极生物电阻抗分析方法来评估其临床适用性。测量了全身电阻、电抗和阻抗，并与30名年龄和性别匹配的健康志愿者的相应指标进行比较。腹水型肝硬化患者（电阻 = 461±80Ω；阻抗 = 462±80Ω）和非腹水型肝硬化患者（电阻 = 487±96Ω；阻抗 = 489±97Ω）的电阻和阻抗值与对照组（电阻 = 488±44Ω；阻抗 = 491±44Ω）相当。然而，与健康受试者（56±7Ω）相比，腹水患者和无腹水患者的全身电抗均显著降低（p < 0.05）（分别为34±9Ω和47±12Ω）。对10例腹水患者在腹腔穿刺术前和术后均测定了全身水含量；抽出的腹腔内液体量（7.9±3.8 L）无法完全解释清楚，仅检测到平均量为1.9±1.0 L，且与初始腹水量无关。我们的数据清楚地表明，四极生物电阻抗分析不足以测量腹部“分隔化”液体的变化。
