Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA 98195, USA.
Child Neuropsychol. 2010;16(3):255-78. doi: 10.1080/09297041003601454. Epub 2010 Mar 18.
We explored social information processing and its relation to social and communicative symptoms in toddlers with Autism Spectrum Disorder (ASD) and their siblings. Toddlers with more severe symptoms of autism showed slower habituation to faces than comparison groups; slower face learning correlated with poorer social skills and lower verbal ability. Unaffected toddlers who were siblings of children with ASD also showed slower habituation to faces compared with toddlers without siblings with ASD. We conclude that slower rates of face learning may be an endophenotype of ASD and is associated with more severe symptoms among affected individuals.
我们探究了自闭症谱系障碍(ASD)幼儿及其兄弟姐妹的社会信息处理及其与社交和沟通症状的关系。自闭症症状更严重的幼儿对人脸的习惯化速度比对照组慢;较慢的面孔学习与较差的社交技能和较低的语言能力相关。患有 ASD 的儿童的未受影响的兄弟姐妹的幼儿与没有患有 ASD 的兄弟姐妹的幼儿相比,对人脸的习惯化速度也较慢。我们得出结论,较慢的面孔学习速度可能是 ASD 的一个内表型,与受影响个体的更严重症状相关。