Slinko Vicki G, McCall Bradley J, Stafford Russell J, Bell Robert J, Hiley Lester A, Sandberg Sofie M, White Sue A, Bell Kerry M
Brisbane Southside Population Health Unit, Archerfield, Queensland.
Commun Dis Intell Q Rep. 2009 Dec;33(4):419-25.
This paper describes outbreaks of Salmonella Typhimurium phage type 197 (STm197) linked to eggs from the farm of a single egg producer. Epidemiological and microbiological investigations (genotyping by multiple locus variable number tandem repeats analysis [MLVA]) identified outbreaks of STm197 with the same or closely-related MLVA profiles in a series of restaurants across Brisbane over 2 months. Environmental health investigations revealed that these restaurants were supplied with eggs from the same egg producer and that cross-contamination may have contributed to the outbreak. Environmental swabs taken from restaurant kitchens and the farm of the egg producer identified a number of salmonellas including STm197, many with MLVA profiles matching or closely related to the human strains from outbreak cases. A case-to-case comparison study showed a significant association between illness with 1 MLVA type and attending a restaurant during the 5 days before onset of illness (odds ratio [OR] 8.1, 95% confidence interval [CI] 1.8, 35.4). MLVA has become a valuable tool for S. Typhimurium surveillance and outbreak investigation. This outbreak further justifies the Commonwealth Government's decision to develop a draft national primary production and processing standard for eggs and egg products to address food safety risks posed by cracked and dirty eggs.
本文描述了与单一蛋类生产商农场的鸡蛋相关的鼠伤寒沙门氏菌197型噬菌体（STm197）疫情。流行病学和微生物学调查（通过多位点可变数目串联重复序列分析[MLVA]进行基因分型）确定，在两个月内，布里斯班一系列餐厅爆发了具有相同或密切相关MLVA图谱的STm197疫情。环境卫生调查显示，这些餐厅的鸡蛋均来自同一蛋类生产商，交叉污染可能是疫情爆发的原因。从餐厅厨房和蛋类生产商农场采集的环境拭子检测出多种沙门氏菌，包括STm197，其中许多菌株的MLVA图谱与疫情病例中的人类菌株相匹配或密切相关。一项病例对照研究表明，感染一种MLVA类型疾病与发病前5天内在餐厅就餐之间存在显著关联（优势比[OR] 8.1，95%置信区间[CI] 1.8，35.4）。MLVA已成为鼠伤寒沙门氏菌监测和疫情调查的重要工具。此次疫情进一步证明了英联邦政府制定鸡蛋和蛋制品国家初级生产和加工标准草案以应对破损和脏污鸡蛋带来的食品安全风险这一决定的合理性。
