Ford Laura, Wang Qinning, Stafford Russell, Ressler Kelly-Anne, Norton Sophie, Shadbolt Craig, Hope Kirsty, Franklin Neil, Krsteski Radomir, Carswell Adrienne, Carter Glen P, Seemann Torsten, Howard Peter, Valcanis Mary, Castillo Cristina Fabiola Sotomayor, Bates John, Glass Kathryn, Williamson Deborah A, Sintchenko Vitali, Howden Benjamin P, Kirk Martyn D
1 National Centre for Epidemiology and Population Health, Research School of Population Health, The Australian National University , Canberra, Australia .
2 OzFoodNet, Health Protection Service , Population Health Protection and Prevention, ACT Health, Canberra, Australia .
Foodborne Pathog Dis. 2018 May;15(5):285-292. doi: 10.1089/fpd.2017.2353. Epub 2018 Mar 20.
Salmonella Typhimurium is a common cause of foodborne illness in Australia. We report on seven outbreaks of Salmonella Typhimurium multilocus variable-number tandem-repeat analysis (MLVA) 03-26-13-08-523 (European convention 2-24-12-7-0212) in three Australian states and territories investigated between November 2015 and March 2016. We identified a common egg grading facility in five of the outbreaks. While no Salmonella Typhimurium was detected at the grading facility and eggs could not be traced back to a particular farm, whole genome sequencing (WGS) of isolates from cases from all seven outbreaks indicated a common source. WGS was able to provide higher discriminatory power than MLVA and will likely link more Salmonella Typhimurium cases between states and territories in the future. National harmonization of Salmonella surveillance is important for effective implementation of WGS for Salmonella outbreak investigations.
鼠伤寒沙门氏菌是澳大利亚食源性疾病的常见病因。我们报告了2015年11月至2016年3月期间在澳大利亚三个州和领地调查的7起鼠伤寒沙门氏菌多位点可变数目串联重复序列分析（MLVA）03-26-13-08-523（欧洲标准2-24-12-7-0212）疫情。我们在其中5起疫情中发现了一个共同的鸡蛋分级设施。虽然在分级设施中未检测到鼠伤寒沙门氏菌，且鸡蛋无法追溯到特定农场，但对所有7起疫情病例分离株的全基因组测序（WGS）表明存在共同来源。WGS能够提供比MLVA更高的鉴别力，未来可能会将更多州和领地之间的鼠伤寒沙门氏菌病例联系起来。全国沙门氏菌监测的协调统一对于有效实施WGS进行沙门氏菌疫情调查很重要。
