Detroit Medical Center and Michigan State College of Osteopathic Medicine, Detroit, Michigan 48201, USA.
J Urol. 2010 May;183(5):1859-62. doi: 10.1016/j.juro.2010.01.020. Epub 2010 Mar 29.
We evaluated the success rate of direct vision internal urethrotomy as a treatment for simple male urethral strictures.
A retrospective chart review was performed on 136 patients who underwent urethrotomy from January 1994 through March 2009. The Kaplan-Meier method was used to analyze stricture-free probability after the first, second, third, fourth and fifth urethrotomy. Patients with complex strictures (36) were excluded from the study for reasons including previous urethroplasty, neophallus or previous radiation, and 24 patients were lost to followup.
Data were available for 76 patients. The stricture-free rate after the first urethrotomy was 8% with a median time to recurrence of 7 months. For the second urethrotomy stricture-free rate was 6% with a median time to recurrence of 9 months. For the third urethrotomy stricture-free rate was 9% with a median time to recurrence of 3 months. For procedures 4 and 5 stricture-free rate was 0% with a median time to recurrence of 20 and 8 months, respectively.
Urethrotomy is a popular treatment for male urethral strictures. However, the performance characteristics are poor. Success rates were no higher than 9% in this series for first or subsequent urethrotomy during the observation period. Most of the patients in this series will be expected to experience failure with longer followup and the expected long-term success rate from any (1 through 5) urethrotomy approach is 0%. Urethrotomy should be considered a temporizing measure until definitive curative reconstruction can be planned.
我们评估直接视觉尿道内切开术作为治疗单纯男性尿道狭窄的成功率。
对 1994 年 1 月至 2009 年 3 月期间进行尿道切开术的 136 例患者进行了回顾性图表分析。采用 Kaplan-Meier 法分析第一次、第二次、第三次、第四次和第五次尿道切开术后无狭窄概率。由于先前的尿道成形术、新阴茎或先前的放疗等原因,将 36 例复杂狭窄患者排除在研究之外,24 例患者失访。
76 例患者的数据可用。第一次尿道切开术的无狭窄率为 8%,复发中位时间为 7 个月。第二次尿道切开术的无狭窄率为 6%,复发中位时间为 9 个月。第三次尿道切开术的无狭窄率为 9%,复发中位时间为 3 个月。第四次和第五次尿道切开术的无狭窄率分别为 0%,复发中位时间分别为 20 个月和 8 个月。
尿道切开术是治疗男性尿道狭窄的一种常用方法。然而,其性能特征较差。在观察期间,本系列中第一次或后续尿道切开术的成功率均不高于 9%。该系列中的大多数患者预计在随访时间延长后会失败,任何(1 至 5 次)尿道切开术的预期长期成功率均为 0%。尿道切开术应被视为一种临时措施,直到可以计划进行确定性的治愈性重建。