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男性尿道狭窄疾病中尿道成形术的使用增加:对2006年至2023年德国住院干预措施的分析

Increasing utilization of urethroplasty for male urethral stricture disease: analysis of in-hospital interventions in Germany from 2006 to 2023.

作者信息

Herout Roman, Flegar Luka, Putz Juliane, Eisenmenger Nicole, Huber Johannes, Thomas Christian, Baunacke Martin

机构信息

Department of Urology, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, Fetscherstraße 74, 01307, Dresden, Germany.

Department of Urology, Philipps-University Marburg, Marburg, Germany.

出版信息

Int Urol Nephrol. 2025 Apr 28. doi: 10.1007/s11255-025-04487-1.

DOI:10.1007/s11255-025-04487-1
PMID:40295328
Abstract

PURPOSE

There is a wide range of surgical treatments for urethral strictures. There is no information on the extent to which these procedures have been used over the past few years.

METHODS

We analyzed data from Diagnosis Related Groups (DRG) billing data from DESTATIS. Linear regression models were utilized for the analysis of trends over time.

RESULTS

A significant decrease of male urethral stricture cases during the study period was observed. Cases decreased from 48,020 cases in 2006 to 33,062 cases in 2023, i.e. -31%. This decline was mainly driven by the decrease in cases in the younger age group (≤ 79 years), whereas a significant increase was noted in octogenarians (+ 24%). A total of 834,476 procedures for urethral stricture disease were analyzed. In accordance with total case numbers, inpatient surgical interventions for urethral stricture disease decreased by 39% during the study period. Internal urethrotomy significantly decreased by 50% (from 41,443 in 2006 to 20,777 in 2023; p < 0.001). Likewise, urethral dilatations significantly decreased by 17% (from 14,134 in 2006 to 11,674 in 2023; p = 0.002). On the contrary, urethroplasties significantly increased by 156% (from 873 in 2006 to 2,239 in 2023; p < 0.001).

CONCLUSION

We present contemporary data on urethral stricture disease management in Germany. Case numbers of internal urethrotomies and urethral dilatations are declining while urethroplasty is increasingly utilized as a definitive treatment for urethral stricture disease. This may reflect an optimized treatment of urethral strictures with more urethroplasties and thus fewer relapses to be treated.

摘要

目的

尿道狭窄有多种手术治疗方法。过去几年中这些手术的使用程度尚无相关信息。

方法

我们分析了德国联邦统计局(DESTATIS)诊断相关分组(DRG)计费数据。采用线性回归模型分析随时间的趋势。

结果

在研究期间观察到男性尿道狭窄病例显著减少。病例数从2006年的48,020例降至2023年的33,062例,即下降了31%。这种下降主要是由较年轻年龄组(≤79岁)病例数的减少所驱动,而八旬老人的病例数显著增加(+24%)。共分析了834,476例尿道狭窄疾病手术。与总病例数一致,研究期间尿道狭窄疾病的住院手术干预减少了39%。尿道内切开术显著减少了50%(从2006年的41,443例降至2023年的20,777例;p<0.001)。同样,尿道扩张术显著减少了17%(从2006年的14,134例降至2023年的11,674例;p = 0.002)。相反,尿道成形术显著增加了156%(从2006年的873例增至2023年的2,239例;p<0.001)。

结论

我们提供了德国尿道狭窄疾病管理的当代数据。尿道内切开术和尿道扩张术的病例数在下降,而尿道成形术越来越多地被用作尿道狭窄疾病的确定性治疗方法。这可能反映了尿道狭窄治疗的优化,尿道成形术增多,因此需要治疗的复发病例减少。

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本文引用的文献

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Decision regret and long-term success rates after ventral buccal mucosa graft urethroplasty.腹侧颊黏膜移植尿道成形术后的决策后悔与长期成功率
BJU Int. 2025 Feb;135(2):303-309. doi: 10.1111/bju.16566. Epub 2024 Oct 21.
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National Trends in the Management of Urethral Stricture Disease.尿道狭窄疾病管理的全国趋势
Urol Pract. 2020 Nov;7(6):541-546. doi: 10.1097/UPJ.0000000000000134. Epub 2020 Jan 7.
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Holmium: YAG Versus Cold Knife Internal Urethrotomy in the Management of Short Urethral Strictures: A Randomized Controlled Trial.钬激光与冷刀内尿道切开术治疗短段尿道狭窄的随机对照试验
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Endoscopic treatments prior to urethroplasty: trends in management of urethral stricture disease.尿道成形术前的内镜治疗:尿道狭窄疾病治疗管理的趋势。
BMC Urol. 2020 Jun 13;20(1):68. doi: 10.1186/s12894-020-00638-x.
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Trends in urethral stricture management over two decades.二十年来尿道狭窄治疗的趋势。
BJU Int. 2019 Nov;124 Suppl 1:37-41. doi: 10.1111/bju.14875. Epub 2019 Oct 22.
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The Impact of Age on Urethroplasty Success.年龄对尿道成形术成功率的影响。
Urology. 2017 Sep;107:232-238. doi: 10.1016/j.urology.2017.03.066. Epub 2017 Jun 1.
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Is there a way to predict failure after direct vision internal urethrotomy for single and short bulbar urethral strictures?对于单一且短段的球部尿道狭窄,直视下尿道内切开术后是否存在预测失败的方法?
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Visual Internal Urethrotomy for Adult Male Urethral Stricture Has Poor Long-Term Results.成年男性尿道狭窄的可视内部尿道切开术长期效果不佳。
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