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加温罗哌卡因对硬膜外感觉阻滞特征的体温影响。

The effect of warmed ropivacaine to body temperature on epidural sensory block characteristics.

机构信息

Department of Anesthesiology, Chang Gung Memorial Hospital, Linkou, Taiwan.

出版信息

J Clin Anesth. 2010 Mar;22(2):110-4. doi: 10.1016/j.jclinane.2009.03.014.

Abstract

STUDY OBJECTIVE

To determine whether warmed (body temperature) ropivacaine increases the speed of onset of sensory block of epidural anesthesia.

STUDY DESIGN

Prospective, randomized, double-blind study.

SETTING

University hospital.

PATIENTS

180 ASA physical status I and II patients, aged 18 to 64 years, undergoing elective anal surgery.

INTERVENTIONS

Patients were randomly divided into 6 groups defined by ropivacaine temperature [room temperature (RT) or body temperature (BT)] and concentration (0.5%, 0.75%, or 1.0%).

MEASUREMENTS

Sensory block was evaluated by pinprick at the T10, T12, L3, and the perianal region (S4, S5) dermatomes. pH values and adverse events were also recorded.

MAIN RESULTS

There were no differences in baseline demographics, pH, or upper sensory level between groups. Mean onset time of T12 and L3 sensory block was significantly faster for each BT than RT ropivacaine concentration. Anal region (S4, S5) sensory block was significantly faster after BT 0.75% versus RT 0.75% ropivacaine.

CONCLUSIONS

Warmed ropivacaine shortens the onset of sensory block of epidural anesthesia.

摘要

研究目的

确定加温(体温)罗哌卡因是否会加快硬膜外麻醉感觉阻滞的起效速度。

研究设计

前瞻性、随机、双盲研究。

地点

大学医院。

患者

180 名 ASA 身体状况 I 和 II 级、年龄在 18 至 64 岁之间的择期肛门手术患者。

干预措施

患者随机分为 6 组,按罗哌卡因温度[室温(RT)或体温(BT)]和浓度(0.5%、0.75%或 1.0%)定义。

测量

通过刺痛评估 T10、T12、L3 和肛周区域(S4、S5)皮区的感觉阻滞。还记录了 pH 值和不良事件。

主要结果

各组间基线人口统计学、pH 值或上感觉水平无差异。BT 罗哌卡因浓度的 T12 和 L3 感觉阻滞的平均起效时间明显快于 RT 罗哌卡因浓度。BT 0.75% 罗哌卡因的肛周区域(S4、S5)感觉阻滞明显快于 RT 0.75% 罗哌卡因。

结论

加温罗哌卡因可缩短硬膜外麻醉感觉阻滞的起效时间。

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