Nemours Children's Clinic, Jacksonville, FL, USA.
J Clin Anesth. 2010 Mar;22(2):126-9. doi: 10.1016/j.jclinane.2009.01.017.
The case of an 8 year-old boy undergoing resection of pheochromocytoma, who received a combination of dexmedetomidine and magnesium sulfate (MgSO4) for hemodynamic control, is reported. He was prepared for surgery with phenoxybenzamine and atenolol. Dexmedetomidine was started in the preoperative holding area and, with MgSO4, continuously infused for most of the case. Good cardiovascular stability was achieved, but low-dose esmolol and nicardipine infusions were required during tumor manipulation. There was minimal post-resection hypotension, the neuromuscular block was easily antagonized, and the child's trachea was quickly extubated.
报告了一例 8 岁男孩在接受嗜铬细胞瘤切除术时,使用右美托咪定和硫酸镁(MgSO4)联合进行血流动力学控制的病例。他在手术前准备阶段使用酚芐明和阿替洛尔。右美托咪定在术前等待区开始使用,并与 MgSO4 一起在手术过程中持续输注。实现了良好的心血管稳定性,但在肿瘤操作期间需要低剂量艾司洛尔和尼卡地平输注。术后出现轻微低血压,神经肌肉阻滞剂很容易拮抗,患儿的气管很快被拔出。