Department of Gastroenterology, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai Institute of Digestive Disease, Shanghai, People's Republic of China.
Gastrointest Endosc. 2010 Jul;72(1):103-8. doi: 10.1016/j.gie.2009.12.003. Epub 2010 Mar 20.
The methods for increasing the rate of complete small-bowel examinations by capsule endoscopy (CE) demonstrate conflicting results, and it is unknown whether improving the completion rate of CE transit is correlated with improvement in diagnostic yield.
The aim of this study was to determine whether a higher rate of complete small-bowel examinations results in a higher diagnostic yield of CE.
Case-control comparison.
Tertiary care university hospital.
A total of 273 patients underwent conventional CE (group A), and 261 patients underwent real-time CE (group B). Furthermore, the patients in groups A and B were divided into 2 subgroups by pyloric transit time (A1, A2 and B1, B2, respectively).
After swallowing the capsule, each patient was monitored with a real-time viewer in group B, and the patients underwent endoscopic placement if the capsule was delayed in the esophagus or stomach.
Pyloric transit time, small-bowel transit time, the rate of complete small-bowel examinations, and the diagnostic yield.
The rate of complete small-bowel examinations was significantly higher in group B than in group A (87.4% vs 78.0%, respectively; P = .004). The diagnostic yield was significantly higher in group B2 than in group A2 (60.0% vs 41.7%, respectively; P = .019).
Nonrandomized study.
Endoscopic placement improves the rate of complete small-bowel examinations, resulting in a higher diagnostic yield of CE.
胶囊内镜（CE）提高全小肠检查完成率的方法显示出相互矛盾的结果，目前尚不清楚提高 CE 传输完成率是否与诊断率的提高相关。
本研究旨在确定全小肠检查完成率的提高是否会导致 CE 的诊断率提高。
病例对照比较。
三级护理大学医院。
共有 273 例患者接受常规 CE（A 组），261 例患者接受实时 CE（B 组）。此外，A 组和 B 组的患者根据幽门通过时间进一步分为 2 个子组（分别为 A1、A2 和 B1、B2）。
吞下胶囊后，B 组的每位患者均通过实时查看器进行监测，如果胶囊在食管或胃中延迟，患者将接受内镜放置。
幽门通过时间、小肠通过时间、全小肠检查完成率和诊断率。
B 组的全小肠检查完成率明显高于 A 组（分别为 87.4%和 78.0%；P =.004）。B2 组的诊断率明显高于 A2 组（分别为 60.0%和 41.7%；P =.019）。
非随机研究。
内镜放置可提高全小肠检查完成率，从而提高 CE 的诊断率。
