The PACE Clinic, ORYGEN Youth Health, Parkville, Melbourne, Australia.
Psychiatry Res. 2010 May 15;177(1-2):84-91. doi: 10.1016/j.psychres.2010.02.011. Epub 2010 Mar 21.
Individuals at "ultra high risk" (UHR) for psychosis have been found to experience high rates of sexual trauma. An aetiological role for sexual trauma has been proposed for psychotic disorders and may influence psychotic symptom content. We aimed to investigate the relationship between previous sexual trauma and reported psychotic-like experiences, in particular psychotic symptoms with a sexual content in a UHR sample. We investigated the prevalence of "attenuated" or "subthreshold" psychotic symptoms with a sexual content in a consecutive series of patients recruited to a specialist UHR clinic. Patient's experience of general and sexual trauma was rated separately using a trauma questionnaire based on the list of events qualifying as traumas under DSM IV. The sample consisted of 92 patients, 14 (15.2%) had experienced an attenuated psychotic symptom with sexual content. The most common symptom was overvalued ideas/delusions of being watched in the shower/toilet or undressing. A considerable proportion of the sample (36.2%) had experienced sexual trauma (sexually molested or raped). Presence of attenuated psychotic symptoms with sexual content was related to history of previous sexual trauma (OR 7.17, P<0.01). This relationship remained significant when other traumatic experiences, PTSD diagnosis, age and sex were adjusted for. Further research into this relationship with regard to outcome and treatment is warranted.
个体处于精神病的“超高风险”(UHR)状态被发现具有较高的性创伤发生率。性创伤在精神病性障碍中具有病因学作用,并可能影响精神病症状的内容。我们旨在调查超高危人群中既往性创伤与报告的类精神病体验之间的关系,特别是与性内容相关的精神病症状。我们调查了连续系列患者中“减弱”或“亚阈值”与性内容相关的精神病症状的患病率,这些患者是专门的 UHR 诊所招募的。使用基于 DSM-IV 中合格创伤事件清单的创伤问卷,分别评估患者的一般和性创伤经历。该样本由 92 名患者组成,其中 14 名(15.2%)经历了有性内容的减弱型精神病症状。最常见的症状是被过度重视的想法/被监视洗澡/上厕所或脱衣服的妄想。相当一部分患者(36.2%)经历过性创伤(被性虐待或强奸)。具有性内容的减弱型精神病症状的存在与既往性创伤史有关(OR 7.17,P<0.01)。当调整其他创伤经历、创伤后应激障碍诊断、年龄和性别时,这种关系仍然显著。需要进一步研究这种关系与结果和治疗的关系。