University of Padova, Centre of Mechanics of Biological Materials, Via F. Marzolo 9, I-35131 Padova, Italy.
Med Eng Phys. 2010 Jun;32(5):516-22. doi: 10.1016/j.medengphy.2010.02.018. Epub 2010 Mar 20.
This paper presents a visco-hyperelastic constitutive model developed to describe the biomechanical response of heel pad tissues. The model takes into account the typical features of the mechanical response such as large displacement, strain phenomena, and non-linear elasticity together with time-dependent effects. The constitutive model was formulated, starting from the analysis of the complex structural and micro-structural configuration of the tissues, to evaluate the relationship between tissue histology and mechanical properties. To define the constitutive model, experimental data from mechanical tests were analyzed. To obtain information about the mechanical response of the tissue so that the constitutive parameters could be established, data from both in vitro and in vivo tests were investigated. Specifically, the first evaluation of the constitutive parameters was performed by a coupled deterministic and stochastic optimization method, accounting for data from in vitro tests. The comparison of constitutive model results and experimental data confirmed the model's capability to describe the compression behaviour of the heel pad tissues, regarding both constant strain rate and stress relaxation tests. Based on the data from additional experimental tests, some of the constitutive parameters were modified in order to interpret the in vivo mechanical response of the heel pad tissues. This approach made it possible to interpret the actual mechanical function of the tissues.
本文提出了一种粘弹性本构模型,用于描述足跟垫组织的生物力学响应。该模型考虑了典型的力学响应特征,如大位移、应变现象和非线性弹性以及时变效应。本构模型的构建从组织的复杂结构和微观结构配置分析开始,以评估组织组织学和力学性能之间的关系。为了定义本构模型,对力学试验的实验数据进行了分析。为了获得组织力学响应的信息,以便建立本构参数,研究了体外和体内试验的数据。具体而言,通过考虑体外试验数据的确定性和随机优化方法对本构参数进行了首次评估。本构模型结果与实验数据的比较证实了该模型能够描述足跟垫组织的压缩行为,包括恒应变速率和应力松弛试验。基于额外实验测试的数据,对一些本构参数进行了修改,以解释足跟垫组织的体内力学响应。这种方法使得解释组织的实际力学功能成为可能。