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Keeping sphingolipid levels nORMal.

作者信息

Walther Tobias C

机构信息

Organelle Architecture and Dynamics, Max Planck Institute of Biochemistry, 82152 Martinsried, Germany.

出版信息

Proc Natl Acad Sci U S A. 2010 Mar 30;107(13):5701-2. doi: 10.1073/pnas.1001503107. Epub 2010 Mar 16.

Abstract
摘要

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本文引用的文献

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Orm1 and Orm2 are conserved endoplasmic reticulum membrane proteins regulating lipid homeostasis and protein quality control.
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Nature. 2010 Feb 25;463(7284):1048-53. doi: 10.1038/nature08787.
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A protein kinase network regulates the function of aminophospholipid flippases.
Proc Natl Acad Sci U S A. 2010 Jan 5;107(1):34-9. doi: 10.1073/pnas.0912497106. Epub 2009 Dec 4.
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A genome-wide screen for genes affecting eisosomes reveals Nce102 function in sphingolipid signaling.
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Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.
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