19283 例新发性麻风病例诊断时发生身体残疾的危险因素。
Risk factors for physical disability at diagnosis of 19,283 new cases of leprosy.
机构信息
Infectious Diseases Branch, School of Medicine, Federal University of Minas Gerais, Brazil.
出版信息
Rev Soc Bras Med Trop. 2010 Jan-Feb;43(1):19-22. doi: 10.1590/s0037-86822010000100005.
INTRODUCTION
The purpose of this study was to evaluate risk factors for physical disability at the moment of leprosy diagnosis.
METHODS
This is a retrospective, descriptive and exploratory investigation of 19,283 patients with leprosy, registered in the State of Minas Gerais, Brazil, between 2000 and 2005.
RESULTS
The risk of Grade 2 disability was 16.5-fold higher in patients with lepromatous leprosy, and 12.8-fold higher in patients presenting the borderline form, compared to patients presenting indeterminate leprosy. The occurrence of more than one thickened nerve increased the odds of a patient developing Grade 2 disability, 8.4-fold. Age <15 years, multibacillary leprosy and no formal education presented 7.0, 5.7 and 5.6 odds of developing physical disability, respectively.
CONCLUSIONS
These factors should be considered as strong prognostic indicators in the development of physical disability at diagnosis.
简介
本研究旨在评估麻风病诊断时发生身体残疾的风险因素。
方法
这是一项回顾性、描述性和探索性研究，共纳入了 19283 名 2000 年至 2005 年在巴西米纳斯吉拉斯州登记的麻风病患者。
结果
瘤型和界限类偏瘤型麻风患者发生 2 级残疾的风险分别是未定型麻风患者的 16.5 倍和 12.8 倍。出现 1 根以上粗大神经的患者发生 2 级残疾的几率增加 8.4 倍。年龄<15 岁、多菌型麻风病和未接受正规教育分别使患者发生身体残疾的几率增加 7.0 倍、5.7 倍和 5.6 倍。
结论
这些因素应被视为诊断时发生身体残疾的强预后指标。
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