Department of Oral Medicine, Carolinas Medical Center, Charlotte, NC 28232-2861, USA.
Support Care Cancer. 2010 Aug;18(8):979-84. doi: 10.1007/s00520-010-0856-3. Epub 2010 Mar 20.
Oral complications are commonly experienced by patients undergoing cancer therapies. The Oral Care Study Group of the Multinational Association of Supportive Care in Cancer/International Society of Oral Oncology (MASCC/ISOO) has completed nine systematic reviews including Bisphosphonate Osteonecrosis of the Jaw, Odontogenic/Periodontal Infection, Dysgeusia, Oral Fungal Infection, Osteoradionecrosis, Trismus, Oral Pain, Oral Viral Infection, and Xerostomia.
The aims of these reviews were to determine the prevalence of each oral complication, relationship with quality of life, economic impact, and formulation of guidelines based on the quality of the literature. The present article described the details of the methodology and statistical analysis utilized in these nine systematic reviews. Additionally, a summary of the quality of the literature from these oral complications is presented.
Oral complications associated with cancer therapies are common among cancer patients. The systematic reviews by the Oral Care Study Group of MASCC/ISOO provide a thorough assessment of the available literature for these oral complications.
癌症治疗患者常经历口腔并发症。多国支持治疗癌症协会/国际口腔肿瘤协会（MASCC/ISOO）口腔护理研究组已完成九项系统评价，包括双膦酸盐颌骨坏死、牙源性/牙周感染、味觉障碍、口腔真菌感染、放射性骨坏死、牙关紧闭、口腔疼痛、口腔病毒感染和口干。
这些综述的目的是确定每种口腔并发症的患病率、与生活质量的关系、经济影响，并根据文献质量制定指南。本文描述了这些系统评价中使用的方法学和统计分析的细节。此外，还介绍了这些口腔并发症文献质量的总结。
癌症治疗相关的口腔并发症在癌症患者中很常见。MASCC/ISOO 口腔护理研究组的系统评价对这些口腔并发症的现有文献进行了全面评估。
