Meyer F B, Meissner I, Fode N C, Losasso T J
Department of Neurologic Surgery, Mayo Clinic, Rochester, MN 55905.
Mayo Clin Proc. 1991 May;66(5):464-9. doi: 10.1016/s0025-6196(12)62385-4.
Between 1971 and 1989, 749 carotid endarterectomies were performed at our institution for symptomatic carotid occlusive disease in patients older than 70 years of age. Of these procedures, 693 were done in patients 71 through 80 years of age, and 56 were done in patients between the ages of 81 and 90 years. The neurologic morbidity and perioperative mortality in the former group were 2.9% and 1.4%, respectively, whereas in the latter group the corresponding values were 5.4% and 0%, respectively. For the entire group, the neurologic morbidity was 3.1% and the mortality was 1.3%. Of the 23 new postoperative neurologic deficits, 19 (83%) occurred in high-risk patients with severe preoperative neurologic or medical risks, and 14 (61%) of these deficits were minor. In selected elderly patients with symptomatic hemodynamically significant carotid occlusive disease, endarterectomy seems to be a safe procedure that is associated with acceptably low perioperative morbidity and mortality.
1971年至1989年间,我院为70岁以上有症状的颈动脉闭塞性疾病患者实施了749例颈动脉内膜切除术。在这些手术中,693例是为71至80岁的患者进行的,56例是为81至90岁的患者进行的。前一组的神经并发症发生率和围手术期死亡率分别为2.9%和1.4%,而后一组相应的值分别为5.4%和0%。对于整个组,神经并发症发生率为3.1%,死亡率为1.3%。在23例新的术后神经功能缺损中,19例(83%)发生在术前有严重神经或医疗风险的高危患者中,其中14例(61%)为轻度缺损。在选定的有症状的、血流动力学上有显著意义的颈动脉闭塞性疾病老年患者中,内膜切除术似乎是一种安全的手术,围手术期发病率和死亡率低至可接受。