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[老年患者的颈动脉内膜切除术。基于594例连续手术的寿命表分析及文献综述]

[Carotid endarterectomy in the elderly patient. Life table analysis and review of the literature based on 594 consecutive operations].

作者信息

Hoffmann A, Schweiger H

机构信息

Chirurgische Universitätsklinik, Erlangen.

出版信息

Langenbecks Arch Chir. 1993;378(5):297-303. doi: 10.1007/BF00183968.

DOI:10.1007/BF00183968
PMID:8412438
Abstract

The significance of age as a prognostic factor was evaluated in patients undergoing carotid artery surgery between 12.8.86 and 31.10.92 in the Department of Vascular Surgery, Erlangen, 594 operations were performed on 546 consecutive patients using somatosensory evoked potentials as routine monitoring. Patients were divided into an older group of 139 (150 operations) with a mean age of 78.2 years and a younger group of 407 (444 operations) with a mean age of 64.4 years. There was no statistical difference in preoperative neurological status and number of risk factors, although there were different distributions of risk factors and concurrent illnesses. Thirty-day mortality rates were 1.7% for younger and 0.7% for older patients, and the incidence of postoperative stroke was 1.7% and 0.7% respectively (not statistically significant). Cumulative 5-year survival was 72.2% and 68.2% respectively. Cardiac diseases were the main cause of death in both groups, mainly fatal cardiac ischemia in younger patients and non-ischemic disease in the older patients. The 5-year stroke-free survival rate was 81% and 91.3% respectively (not significant). There was a trend towards a worse outcome for older patients with stages IIb and IV disease.

摘要

1986年8月12日至1992年10月31日期间,在埃尔朗根血管外科接受颈动脉手术的患者中,评估了年龄作为预后因素的意义。对546例连续患者进行了594次手术,术中使用体感诱发电位作为常规监测。患者分为老年组139例(150次手术),平均年龄78.2岁;年轻组407例(444次手术),平均年龄64.4岁。尽管危险因素和并存疾病的分布不同,但术前神经状态和危险因素数量无统计学差异。年轻患者30天死亡率为1.7%,老年患者为0.7%,术后中风发生率分别为1.7%和0.7%(无统计学意义)。5年累积生存率分别为72.2%和68.2%。两组的主要死亡原因均为心脏病,年轻患者主要为致命性心肌缺血,老年患者主要为非缺血性疾病。5年无中风生存率分别为81%和91.3%(无显著性差异)。IIb期和IV期老年患者的预后有变差的趋势。

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