癌症转移作为治疗靶点。
Cancer metastasis as a therapeutic target.
机构信息
Universitätsmedizin Mannheim, University of Heidelberg, Ludolf-Krehl-Str. 13-17, D-68167 Mannheim, Germany.
出版信息
Eur J Cancer. 2010 May;46(7):1177-80. doi: 10.1016/j.ejca.2010.02.039. Epub 2010 Mar 20.
Abstract
Despite many years of basic and clinical research aimed at curbing tumour growth, metastasis remains the prime reason why cancer patients succumb to their disease. Effective translational research is urgently required, yet is not always easy to achieve. Here we review reasons why metastasis as a disease process has proven difficult to control, and suggest ways in which translational research in this area can be strengthened and advanced.
摘要
尽管多年来一直致力于基础和临床研究以抑制肿瘤生长，但转移仍然是癌症患者最终死于该疾病的主要原因。迫切需要有效的转化研究，但并不总是容易实现。在这里，我们回顾了为什么转移作为一种疾病过程一直难以控制的原因，并提出了加强和推进该领域转化研究的方法。
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