Davies Robert S M, Dawlatly Samir, Clarkson Jeremy R, Bradbury Andrew W, Adam Donald J
University of Birmingham, Department of Vascular Surgery, Heart of England NHS Foundation Trust, Birmingham, United Kingdom.
Vasc Endovascular Surg. 2010 Apr;44(3):170-3. doi: 10.1177/1538574410361972.
To determine the relationship between postoperative renal replacement therapy (RRT) and patient survival after open surgical repair (OR) of ruptured abdominal aortic aneurysm (rAAA).
A retrospective review of consecutive patients who underwent OR for rAAA repair between January 2002 and July 2008 was performed. Early (<30 days) and late (>30 days) outcomes were assessed.
A total of 94 patients (69 men; median [range] age 73.8 [56-89] years) underwent OR of rAAA (infrarenal = 78, juxtarenal = 15, and suprarenal = 1). In-hospital mortality rate was 40% and mean (range) length of intensive care unit (ICU) stay was 9.3 (0-56) days. A total of 23 (24%) patients required postoperative RRT. In-hospital mortality rate was significantly higher (RRT: 87% (20 of 23) vs no RRT: 18 of 71 (25%), P < .0001) and ICU stay significantly longer (RRT: mean (range) days; 14.8 (1-44) vs no RRT: 7.5 (0-56), P = .04) in the RRT patients. On multivariate analysis, RRT (P = .0053) and/or inotropic support (P = .0033) were independent risk factors for death within 30 days of the index procedure.
Renal replacement therapy following OR of rAAA is an independent risk factor for mortality.
确定腹主动脉瘤破裂(rAAA)开放手术修复(OR)后术后肾脏替代治疗(RRT)与患者生存率之间的关系。
对2002年1月至2008年7月期间接受rAAA修复OR的连续患者进行回顾性研究。评估早期(<30天)和晚期(>30天)结果。
共有94例患者(69例男性;中位[范围]年龄73.8[56 - 89]岁)接受了rAAA的OR(肾下型 = 78例,肾旁型 = 15例,肾上型 = 1例)。住院死亡率为40%,重症监护病房(ICU)平均(范围)住院时间为9.3(0 - 56)天。共有23例(24%)患者需要术后RRT。RRT患者的住院死亡率显著更高(RRT:87%(23例中的20例) vs 非RRT:71例中的18例(25%),P <.0001),ICU住院时间显著更长(RRT:平均(范围)天数;14.8(1 - ) vs 非RRT:7.5(0 - 56),P =.04)。多因素分析显示,RRT(P =.0053)和/或血管活性药物支持(P =.0033)是指数手术后30天内死亡的独立危险因素。
rAAA的OR术后肾脏替代治疗是死亡率的独立危险因素。