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腹主动脉瘤破裂开放手术修复后需要肾脏替代治疗的患者的预后。

Outcome in patients requiring renal replacement therapy after open surgical repair for ruptured abdominal aortic aneurysm.

作者信息

Davies Robert S M, Dawlatly Samir, Clarkson Jeremy R, Bradbury Andrew W, Adam Donald J

机构信息

University of Birmingham, Department of Vascular Surgery, Heart of England NHS Foundation Trust, Birmingham, United Kingdom.

出版信息

Vasc Endovascular Surg. 2010 Apr;44(3):170-3. doi: 10.1177/1538574410361972.

Abstract

OBJECTIVE

To determine the relationship between postoperative renal replacement therapy (RRT) and patient survival after open surgical repair (OR) of ruptured abdominal aortic aneurysm (rAAA).

METHODS

A retrospective review of consecutive patients who underwent OR for rAAA repair between January 2002 and July 2008 was performed. Early (<30 days) and late (>30 days) outcomes were assessed.

RESULTS

A total of 94 patients (69 men; median [range] age 73.8 [56-89] years) underwent OR of rAAA (infrarenal = 78, juxtarenal = 15, and suprarenal = 1). In-hospital mortality rate was 40% and mean (range) length of intensive care unit (ICU) stay was 9.3 (0-56) days. A total of 23 (24%) patients required postoperative RRT. In-hospital mortality rate was significantly higher (RRT: 87% (20 of 23) vs no RRT: 18 of 71 (25%), P < .0001) and ICU stay significantly longer (RRT: mean (range) days; 14.8 (1-44) vs no RRT: 7.5 (0-56), P = .04) in the RRT patients. On multivariate analysis, RRT (P = .0053) and/or inotropic support (P = .0033) were independent risk factors for death within 30 days of the index procedure.

CONCLUSIONS

Renal replacement therapy following OR of rAAA is an independent risk factor for mortality.

摘要

目的

确定腹主动脉瘤破裂(rAAA)开放手术修复(OR)后术后肾脏替代治疗(RRT)与患者生存率之间的关系。

方法

对2002年1月至2008年7月期间接受rAAA修复OR的连续患者进行回顾性研究。评估早期(<30天)和晚期(>30天)结果。

结果

共有94例患者(69例男性;中位[范围]年龄73.8[56 - 89]岁)接受了rAAA的OR(肾下型 = 78例,肾旁型 = 15例,肾上型 = 1例)。住院死亡率为40%,重症监护病房(ICU)平均(范围)住院时间为9.3(0 - 56)天。共有23例(24%)患者需要术后RRT。RRT患者的住院死亡率显著更高(RRT:87%(23例中的20例) vs 非RRT:71例中的18例(25%),P <.0001),ICU住院时间显著更长(RRT:平均(范围)天数;14.8(1 - ) vs 非RRT:7.5(0 - 56),P =.04)。多因素分析显示,RRT(P =.0053)和/或血管活性药物支持(P =.0033)是指数手术后30天内死亡的独立危险因素。

结论

rAAA的OR术后肾脏替代治疗是死亡率的独立危险因素。

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