Laboratory of Physiology and Biokinetic (UNIG Campus V), Itaperuna, Brazil.
Int J Sports Physiol Perform. 2010 Mar;5(1):18-26. doi: 10.1123/ijspp.5.1.18.
The purpose of this study was to evaluate the effects of caffeine ingestion before a resistance exercise session on markers of muscle damage (CK, LDH, ALT, AST) and leukocyte levels.
Fifteen soccer athletes completed two resistance exercise sessions that differed only in the ingestion of caffeine or a placebo preworkout.
CK concentration increased significantly following the caffeine session (415.8+/-62.8 to 542.0+/-73.5) and the placebo session (411.5+/-43.3 to 545.8+/-59.9), with no significant differences between sessions. Similarly, LDH concentration increased significantly following the caffeine session (377.5+/-18.0 to 580.5+/-36.1) and the placebo session (384.8+/-13.9 to 570.4+/-36.1), with no significant differences between sessions. Both sessions resulted in significant increases in the total leukocyte count (caffeine=6.24+/-2.08 to 8.84+/-3.41; placebo=6.36+/-2.34 to 8.77+/-3.20), neutrophils (caffeine=3.37+/-0.13 to 5.15+/-0.28; placebo=3.46+/-0.17 to 5.12+/-0.24), lymphocytes (caffeine=2.19+/-0.091 to 2.78+/-0.10; placebo=2.17+/-0.100 to 2.75+/-0.11), and monocytes (caffeine=0.53+/-0.02 to 0.72+/-0.06; placebo=0.56+/-0.03 to 0.69+/-0.04), with no significant differences between sessions.
Ingestion of caffeine at 4.5 mg/kg(-1) did not augment markers of muscle damage or leukocyte levels above that which occurs through resistance exercise alone.
本研究旨在评估在抗阻运动前摄入咖啡因对肌肉损伤标志物（CK、LDH、ALT、AST）和白细胞水平的影响。
15 名足球运动员完成了两次抗阻运动，唯一的区别是运动前摄入咖啡因或安慰剂。
咖啡因组（415.8+/-62.8 至 542.0+/-73.5）和安慰剂组（411.5+/-43.3 至 545.8+/-59.9）的 CK 浓度在运动后均显著升高，且两组间无显著差异。同样，LDH 浓度在咖啡因组（377.5+/-18.0 至 580.5+/-36.1）和安慰剂组（384.8+/-13.9 至 570.4+/-36.1）中均显著升高，且两组间无显著差异。两个试验组的白细胞总数（咖啡因组=6.24+/-2.08 至 8.84+/-3.41；安慰剂组=6.36+/-2.34 至 8.77+/-3.20）、中性粒细胞（咖啡因组=3.37+/-0.13 至 5.15+/-0.28；安慰剂组=3.46+/-0.17 至 5.12+/-0.24）、淋巴细胞（咖啡因组=2.19+/-0.091 至 2.78+/-0.10；安慰剂组=2.17+/-0.100 至 2.75+/-0.11）和单核细胞（咖啡因组=0.53+/-0.02 至 0.72+/-0.06；安慰剂组=0.56+/-0.03 至 0.69+/-0.04）均显著升高，但两组间无显著差异。
摄入 4.5mg/kg(-1)的咖啡因并未增加肌肉损伤标志物或白细胞水平，超过单独抗阻运动所引起的水平。
