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[鼻病毒感染的发病机制]

[Pathogenesis of rhinovirus infection].

作者信息

Dreĭzin R S, Ponomareva T I, Klimanskaia E V, Bektemirov T A, Vikhnovich E M

出版信息

Vopr Virusol. 1977 Nov-Dec(6):716-24.

PMID:203113
Abstract

Rhinoviruses (RV) are the etiological factors of not only acute respiratory diseases of the common cold type but also of acute and chronic diseases of otorhinolaryngological organs. Virological and bacteriological examinations of patients with chronic pneumonia in the stages of exacerbation and incomplete remission revealed a high degree of the infection activity. Virus-bacterial associations were frequently found. RV were isolated from the lower respiratory tract (bronchopulmonary secrete, biopsy materials). The association of RV with the involvement of the lower respiratory tract in patients with chronic pneumonia was demonstrated. Rhinoviremia was detected in one child dying with acute respiratory disease. The results of studies on some factors of specific and nonspecific immunity in patients with chronic pneumonia are presented.

摘要

鼻病毒(RV)不仅是普通感冒型急性呼吸道疾病的病因,也是耳鼻咽喉器官急慢性疾病的病因。对处于病情加重期和不完全缓解期的慢性肺炎患者进行病毒学和细菌学检查,发现感染活性程度很高。经常发现病毒 - 细菌联合体。从下呼吸道(支气管肺分泌物、活检材料)中分离出了鼻病毒。证实了慢性肺炎患者中鼻病毒与下呼吸道受累之间的关联。在一名死于急性呼吸道疾病的儿童中检测到了鼻病毒血症。本文介绍了对慢性肺炎患者特异性和非特异性免疫的一些因素的研究结果。

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