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儿童纤维肌痛;诊断与治疗。

Fibromyalgia in children; diagnosis and treatment.

作者信息

Romano T J

出版信息

W V Med J. 1991 Mar;87(3):112-4.

PMID:2031345
Abstract

Fifteen children (16 years and younger, 10 females, 5 males, mean age 13 years) with juvenile primary fibromyalgia syndrome (JPFS) were seen in a private rheumatology practice over two years. This represented 45 percent of the total number of pediatric rheumatology patients. Symptoms included polymyalgias, polyarthralgias, nonrestorative sleep, difficulty concentrating in school and fatigue. Examination revealed typical tender points, absence of joint swelling, synovitis or nodules and absence of neurological findings. Dolorimetry was abnormal and standard laboratory tests were normal. Most of these patients (67 percent) had seen three or more doctors prior to their rheumatological evaluation and not (60 percent) were told they had juvenile chronic arthritis. Other diagnoses offered were "growing pains" (20 percent), hysteria (7 percent) and psychological problems (7 percent). None of the JPFS patients responded to salicylate or other anti-inflammatory medication. Most (73 percent) responded to cyclobenzaprine, mean dose 12.75 mg. (range 5-25 mg. qhs). JPFS is a very common pediatric rheumatologic problem and is confused with other disorders. Reassurance is very important in the therapy since many parents are fearful that their children may have a potentially crippling disorder. Medication, especially with tricyclics, moderate exercise and proper sleep are also mainstays of therapy.

摘要

在两年时间里,一家私人风湿病诊所接待了15名患有青少年原发性纤维肌痛综合征(JPFS)的儿童(年龄在16岁及以下,10名女性,5名男性,平均年龄13岁)。这占儿科风湿病患者总数的45%。症状包括多肌痛、多关节痛、睡眠恢复不佳、在学校难以集中注意力和疲劳。检查发现有典型的压痛点,无关节肿胀、滑膜炎或结节,且无神经系统体征。痛觉测量异常,标准实验室检查正常。这些患者中的大多数(67%)在接受风湿病评估之前已经看过三名或更多医生,而且其中60%的人曾被告知患有青少年慢性关节炎。其他给出的诊断是“生长痛”(20%)、癔症(7%)和心理问题(7%)。没有一名JPFS患者对水杨酸盐或其他抗炎药物有反应。大多数患者(73%)对环苯扎林有反应,平均剂量为12.75毫克(范围为每晚5 - 25毫克)。JPFS是一种非常常见的儿科风湿病问题,常与其他疾病相混淆。在治疗中给予 reassurance 非常重要,因为许多家长担心他们的孩子可能患有一种潜在致残的疾病。药物治疗,尤其是三环类药物、适度运动和适当睡眠也是治疗的主要方法。 (注:原文中“reassurance”未翻译完整,推测此处可能是想表达“安抚、 reassurance”之类的意思,具体完整准确含义需结合更多上下文确定)

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