Borsy J, Andrási F, Kósa E
Acta Physiol Acad Sci Hung. 1976;47(4):323-33.
The present state of chemistry, structure-activity relationship and cellular mode of action of gastrointestinal polypeptide hormones (gastrin, secretin, cholecystokinin-pancreozymin, caerulein and bombesin) are reviewed. Possible structure of polypeptide receptors and the mechanism of peptide--receptor interaction are described, and the role of acetylcholine and histamine in secretion discussed. The present data support the hormonal-receptor significance of cyclic nucleotides (cAMP, cGMP) in the cellular regulation of secretion.
本文综述了胃肠多肽激素（胃泌素、促胰液素、胆囊收缩素-促胰酶素、蛙皮素和铃蟾肽）的化学现状、构效关系及细胞作用方式。描述了多肽受体的可能结构及肽-受体相互作用的机制，并讨论了乙酰胆碱和组胺在分泌中的作用。目前的数据支持环核苷酸（cAMP、cGMP）在细胞分泌调节中的激素-受体意义。
