Letts L G, Easson P A, Temple D M, Lap B V, Lim C H, Orr A J, Pasaribu S J, Quessy S N, Williams L R
Arch Int Pharmacodyn Ther. 1977 Nov;230(1):42-52.
A series of monosubstituted phenethanolamines with N-isopropyl and N-tert-butyl substituents has been prepared. A detailed pharmacological study has been made of the beta-adrenergic activity of these materials as the nitrogen substituent and the nature and position of the phenyl substituent were changed, and their selectivity has been determined for beta1- and beta2-adrenoceptors in guinea-pig and cat tissues.
已制备出一系列带有N - 异丙基和N - 叔丁基取代基的单取代苯乙醇胺。随着氮取代基以及苯基取代基的性质和位置发生变化，对这些物质的β - 肾上腺素能活性进行了详细的药理学研究，并测定了它们对豚鼠和猫组织中β1和β2肾上腺素受体的选择性。
