McGregor J M, Barker J N, MacDonald D M
Department of Dermatology, United Medical School (Guy's Campus), London, UK.
Clin Exp Dermatol. 1991 Mar;16(2):131-2. doi: 10.1111/j.1365-2230.1991.tb00325.x.
The development of cutaneous proliferative lesions following renal transplantation has been well documented in the literature. Those lesions most commonly seen include viral warts, actinic keratoses and basal-cell and squamous-cell carcinomata. More recently it has been suggested that melanocyte proliferation, both benign and malignant, may follow renal transplantation, probably as a result of immunosuppression. We report the case of an identical twin who developed numerous benign melanocytic naevi following renal transplantation; no such proliferation of naevi occurred in his identical sibling.
肾移植后皮肤增殖性病变的发展在文献中已有充分记载。最常见的那些病变包括病毒疣、光化性角化病以及基底细胞癌和鳞状细胞癌。最近有人提出,肾移植后可能会出现良性和恶性黑素细胞增殖,这可能是免疫抑制的结果。我们报告了一例同卵双胞胎的病例,该患者在肾移植后出现了大量良性黑素细胞痣;而他的同卵双胞胎兄弟并未出现此类痣的增殖。