Jurincic C, Horlbeck R, Metz K, Klippel K F
Urologische Klinik, Allgemeines Krankenhaus, Celle.
Dtsch Med Wochenschr. 1991 May 24;116(21):816-8. doi: 10.1055/s-2008-1063684.
A 19-year-old and a 50-year-old man who together had cleaned a water-tank as part of their duties in a tank protection and cleaning firm developed that same evening lower abdominal pain, dysuria and haematuria. Cystoscopy revealed haemorrhagic cystitis in both patients, a finding confirmed by bladder mucosa biopsy. 4-chlor-2 methylaniline (concentration less than 1 mg/l) was found in hydrolysed serum of both. This metabolite of the pesticide chlordimeform was also found in the urine of the 51-year-old patient (16 mg/l). The haematuria regressed within two days of the patients having increased their fluid intake. Dysuria improved within a week. It is likely that chlordimeform had previously been transported in the water-tank. In case of haemorrhagic cystitis possibly caused by occupational or other poisoning, serum and urine should always be obtained for toxicological tests.
一名19岁和一名50岁的男子在一家水箱保护和清洁公司工作，当晚他们一起清理水箱后出现下腹部疼痛、排尿困难和血尿。膀胱镜检查显示两名患者均患有出血性膀胱炎，膀胱黏膜活检证实了这一发现。在两名患者的水解血清中均发现了4-氯-2-甲基苯胺（浓度低于1毫克/升）。在51岁患者的尿液中也发现了这种杀虫剂杀虫脒的代谢物（16毫克/升）。在患者增加液体摄入量后的两天内，血尿消退。排尿困难在一周内有所改善。很可能之前杀虫脒已被运输到水箱中。对于可能由职业或其他中毒引起的出血性膀胱炎，应始终采集血清和尿液进行毒理学检测。
