Blanchard T L, Schumacher J, Edwards J F, Varner D D, Lewis R D, Everett K, Joyce J R
Department of Large Animal Medicine and Surgery, Texas Veterinary Medical Center, College of Veterinary Medicine, Texas A&M University, College Station 77843.
J Am Vet Med Assoc. 1991 Mar 15;198(6):1043-4.
A Thoroughbred stallion developed priapism that was unresponsive to medical treatment and lavage of the corpus cavernosum penis with heparinized 0.9% NaCl solution. Three weeks after onset of priapism, the penis was firm and noncompliant, and penile pain sensation and ability to retract the penis were lost. Ultrasonography confirmed thrombosis of the corpus cavernosum penis. The stallion was euthanatized because of poor prognosis for return to breeding soundness. Necropsy revealed enlargement of numerous lymph nodes. The dorsal penile nerves were demyelinated distal to the crura of the penis. A diagnosis of generalized malignant melanoma was made; however, neither metastasis to the vertebral canal nor compression of spinal nerve roots as they exited the vertebral foramen was found. Priapism is a persistent erection without sexual arousal and is initially unassociated with penile paralysis, but if prolonged, leads to irreversible venous occlusion where collecting veins join the cavernous spaces. Damage to the dorsal penile nerves may explain the long-term penile paralysis and loss of sensation that accompanied priapism in this stallion. Priapism unassociated with the use of phenothiazine-derivative tranquilizers is uncommon in horses.
一匹纯种种马发生了阴茎异常勃起，对药物治疗以及用肝素化的0.9%氯化钠溶液冲洗阴茎海绵体均无反应。阴茎异常勃起发作三周后，阴茎坚硬且无弹性，阴茎疼痛感和回缩阴茎的能力丧失。超声检查证实阴茎海绵体血栓形成。由于恢复繁殖健康的预后不佳，该种马被实施安乐死。尸检发现多个淋巴结肿大。阴茎背神经在阴茎脚远端出现脱髓鞘。诊断为全身性恶性黑色素瘤；然而，未发现向椎管转移或脊神经根穿出椎间孔时受到压迫的情况。阴茎异常勃起是一种无性欲唤起的持续性勃起，最初与阴茎麻痹无关，但如果持续时间过长，会导致收集静脉汇入海绵体间隙处出现不可逆的静脉阻塞。阴茎背神经受损可能解释了这匹种马阴茎异常勃起伴随的长期阴茎麻痹和感觉丧失。与使用吩噻嗪衍生物镇静剂无关的阴茎异常勃起在马匹中并不常见。
