Hendricks J C, Kline L R
Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia 19104-6010.
J Appl Physiol (1985). 1991 Mar;70(3):1194-200. doi: 10.1152/jappl.1991.70.3.1194.
Simultaneous recordings of the diaphragmatic electromyogram (EMG) were made from two separate regions of the costal diaphragm in six normal cats. The diaphragmatic activities were always synchronous and the amplitudes and rates of rise were similar during slow-wave sleep. In contrast, during natural rapid-eye-movement (REM) sleep, different activity was often present in the two leads. These differences were in the time of onset and offset, as well as in the amplitude and spike patterns, and occurred in approximately 5-20% of the diaphragmatic bursts averaged over the entire REM sleep period. With respect to eye movement density, the rate of differential activation was higher during periods of high density (26%) than in the absence of eye movements (1%) in the four animals for which these data were available. Differential activation of portions of the costal diaphragm is apparently a normal event of REM sleep. This could result from descending state-specific phasic neuronal activity that bypasses the medullary respiratory generator. Differential activation of portions of the diaphragm could contribute to disordered ventilation during REM sleep.
在六只正常猫的肋膈膜两个不同区域同时记录膈肌肌电图（EMG）。膈肌活动总是同步的，在慢波睡眠期间，其幅度和上升速率相似。相比之下，在自然快速眼动（REM）睡眠期间，两条导联中常常出现不同的活动。这些差异体现在起始和结束时间，以及幅度和峰值模式上，在整个REM睡眠期平均约5 - 20%的膈肌爆发中出现。关于眼动密度，在有眼动数据的四只动物中，高密度期（26%）的差异激活率高于无眼动期（1%）。肋膈膜部分的差异激活显然是REM睡眠的一个正常现象。这可能是由于特定状态下的下行阶段性神经元活动绕过了延髓呼吸发生器所致。膈膜部分的差异激活可能导致REM睡眠期间通气紊乱。
