Neilly J B, Gaipa E A, Maislin G, Pack A I
Center for Sleep and Respiratory Neurobiology, University of Pennsylvania, Philadelphia 19104-4283.
J Appl Physiol (1985). 1991 Oct;71(4):1201-15. doi: 10.1152/jappl.1991.71.4.1201.
Because successive rapid-eye-movement (REM) sleep periods in the night are longer in duration and have more phasic events, ventilation during late REM sleep might be more affected than in earlier episodes. Despite the increase in eye movement density (EMD) in late REM sleep, average minute ventilation was, however, not reduced compared with that in early REM sleep. Decreases in rib cage motion (mean inspiratory flow of the rib cage) in association with increasing EMD were offset by increments in respiratory frequency. Apart from expiratory time, there were no significant changes in the slopes of the relationships between EMD and specific ventilatory components, from early to late REM sleep periods. However, there was an increase in the number of episodes when ventilation was reduced during late REM sleep. Changes in ventilatory pattern during late REM sleep are due to changes in the underlying nature of REM sleep. The ventilatory response during eye movements is, however, subject specific. Some subjects exhibit large decrements in mean inspiratory flow of the rib cage and increments in respiratory frequency during bursts of eye movement, whereas other individuals demonstrate only small changes in these ventilatory parameters.
由于夜间连续快速眼动（REM）睡眠期持续时间更长且有更多的相位事件，REM睡眠后期的通气可能比早期更易受到影响。尽管REM睡眠后期眼动密度（EMD）增加，但与REM睡眠早期相比，平均每分钟通气量并未降低。随着EMD增加，胸廓运动（胸廓平均吸气流量）的减少被呼吸频率的增加所抵消。从REM睡眠早期到后期，除呼气时间外，EMD与特定通气成分之间关系的斜率没有显著变化。然而，REM睡眠后期通气减少的发作次数有所增加。REM睡眠后期通气模式的变化是由于REM睡眠潜在性质的改变。然而，眼动期间的通气反应因个体而异。一些受试者在眼动爆发期间胸廓平均吸气流量大幅下降且呼吸频率增加，而其他个体在这些通气参数上仅有微小变化。
