Kono Taro, Kikuchi Yuji, Groff William Frederick, Sakurai Hiroyuki, Yamaki Takashi
Department of Plastic and Reconstructive Surgery, Tokyo Women's Medical University, Tokyo, Japan.
J Cosmet Laser Ther. 2010 Apr;12(2):87-91. doi: 10.3109/14764171003706091.
Nd:YAG pulsed lasers are used for non-ablative skin tightening treatment. A common drawback of this procedure is pain, which is often intolerable. Pneumatic skin flattening (PSF) is a new technology which alleviates pain in laser treatments. The purpose of this study is to assess the clinical efficacy and pain reduction in Nd:YAG laser skin tightening treatments with PSF compared to Nd:YAG laser skin tightening treatments with cryogen spray cooling (CSC).
Eleven patients were treated on the face with an Nd:YAG laser operated at an energy setting of 30 J/cm(2) and a pulse duration of 50 ms. Half of the face was treated with the Nd:YAG using CSC and the other side was treated with the Nd:YAG using PSF. A comparison of pain elicited from each treatment was done by comparing each patient's VAS pain scoring of the two sides.
Treatment efficacy with CSC and with PSF was identical. The study confirmed significant pain reduction with PSF (p < 0.01). The average pain scores for PSF and CSC were 2.4 and 6.9, respectively. Mild ecchymosis was observed in two patients on the PSF side.
Nd:YAG laser skin tightening treatments with PSF are less painful than Nd:YAG laser skin tightening treatments with CSC; the PSF treatments can be done with minimum side effects.
钕钇铝石榴石（Nd:YAG）脉冲激光用于非剥脱性皮肤紧致治疗。该治疗方法的一个常见缺点是疼痛，这种疼痛通常难以忍受。气动皮肤扁平化（PSF）是一种可减轻激光治疗疼痛的新技术。本研究的目的是评估与使用低温喷雾冷却（CSC）的Nd:YAG激光皮肤紧致治疗相比，使用PSF的Nd:YAG激光皮肤紧致治疗的临床疗效和疼痛减轻情况。
11名患者面部接受Nd:YAG激光治疗，能量设置为30 J/cm²，脉冲持续时间为50毫秒。面部一侧使用CSC联合Nd:YAG激光治疗，另一侧使用PSF联合Nd:YAG激光治疗。通过比较每位患者两侧的视觉模拟评分（VAS）疼痛得分来比较每种治疗引发的疼痛。
CSC和PSF的治疗效果相同。研究证实PSF可显著减轻疼痛（p < 0.01）。PSF和CSC的平均疼痛得分分别为2.4和6.9。在PSF侧有两名患者出现轻度瘀斑。
与使用CSC的Nd:YAG激光皮肤紧致治疗相比，使用PSF的Nd:YAG激光皮肤紧致治疗疼痛较轻；PSF治疗的副作用最小。
