Swanson D L, Dahl M V
Department of Dermatology, University of Minnesota Hospitals, Minneapolis.
J Am Acad Dermatol. 1991 Apr;24(4):580-3. doi: 10.1016/0190-9622(91)70087-i.
Hereditary hemorrhagic telangiectasia is an inherited disorder in which patients may have multiple telangiectases and arteriovenous fistulas in the skin and internal organs. Patients can suffer from a variety of serious clinical complications, including abscess formation. We report two patients in whom neurologic symptoms developed from embolic abscesses, one for whom this complication was fatal. The reported incidence and microbiologic features of this complication are similar to that of endocarditis in patients with valvular heart disease. We believe that patients with hereditary hemorrhagic telangiectasia should receive similar antibacterial prophylaxis for procedures placing them at risk for bacteremia.
遗传性出血性毛细血管扩张症是一种遗传性疾病，患者的皮肤和内脏可能有多处毛细血管扩张和动静脉瘘。患者可能会出现各种严重的临床并发症，包括脓肿形成。我们报告了两名因栓塞性脓肿出现神经症状的患者，其中一名患者因这一并发症死亡。该并发症的报告发病率和微生物学特征与瓣膜性心脏病患者的心内膜炎相似。我们认为，患有遗传性出血性毛细血管扩张症的患者在接受有菌血症风险的手术时，应接受类似的抗菌预防措施。
