Department of Gastroenterology and Hepatology, Erasmus MC, 's Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands.
Psychosomatics. 2010 Mar-Apr;51(2):157-65. doi: 10.1176/appi.psy.51.2.157.
The negative impact of chronic liver disease on health-related quality of life (HRQoL) of patients with chronic liver disease (CLD) has long been established, and treatable physiological or psychological factors may potentially influence HRQoL.
The authors assessed the interrelationships of multiple psychological factors and HRQoL in patients with CLD.
Both direct and indirect relationships among HRQoL, depression, anxiety, coping, and self-efficacy in 164 patients with CLD were assessed.
Depression, largely determined by low self-efficacy and, possibly, by use of maladaptive coping strategies, influenced HRQoL in three groups of liver patients.
HRQoL in CLD patients may be positively affected by enhancing coping and self-efficacy skills, thus improving levels of depression.
慢性肝脏疾病对慢性肝脏疾病（CLD）患者的健康相关生活质量（HRQoL）的负面影响早已确立，可治疗的生理或心理因素可能会对 HRQoL 产生潜在影响。
作者评估了 CLD 患者多种心理因素与 HRQoL 之间的相互关系。
评估了 164 例 CLD 患者的 HRQoL、抑郁、焦虑、应对和自我效能之间的直接和间接关系。
抑郁在很大程度上受自我效能低下的影响，可能还受到适应不良应对策略的影响，这影响了三组肝病人群的 HRQoL。
通过增强应对和自我效能技能，CLD 患者的 HRQoL 可能会受到积极影响，从而降低抑郁水平。
