Pradhan B, Thapa N
Department of ENT and Head and Neck Surgery, Tribhuvan University Teaching Hospital, Kathmandu, Nepal.
Nepal Med Coll J. 2009 Sep;11(3):186-8.
This prospective longitudinal study was done to determine extent of tumor and to highlight the importance of lateral rhinotomy approach for nasopharyngeal angiofibroma. Patients with a diagnosis of nasopharyngeal angiofibroma who underwent surgery in Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu from April, 2004 to Jan 2009 were included in the study. Extent of tumour and surgical approaches were noted in a special form prepared for the study. Fisch Staging system was followed for the extent of tumor. A total number of patients were 23 and all of them were male. Age ranged from 15-30 years with mean age of 18.25 years. All the patients underwent contrast enhanced CTScan. Two patients had stage I tumor, 9 patients had stage II disease, other 12 patients had stage III tumor. Twenty patients were operated by lateral rhinotomy approach. In one patient with the tumour hanging in the oropharynx with a pedical attached to the lateral wall of nasopharynx was removed by peroral route and in another patient with tumour confined to nasopharynx and posterior part of nose was removed by transpalatal approach. One patient who had tumour extention into infratemporal fossa were operated by lateral rhinotomy with inferior sublabial extetention approach. Eleven patients underwent preoperative embolization with gelfoam 48 hours prior to surgery. Most of them had stage III disease and were managed surgically by lateral rhinotomy approach. Lateral rhinotomy approach with or without extention of incision can be used to remove tumours in majority of patients.
本前瞻性纵向研究旨在确定肿瘤范围,并强调外侧鼻切开术治疗鼻咽血管纤维瘤的重要性。纳入2004年4月至2009年1月在加德满都马哈拉杰甘杰的特里布万大学教学医院接受手术的鼻咽血管纤维瘤患者。肿瘤范围和手术方式以专门为本研究准备的表格记录。肿瘤范围采用菲施分期系统。患者总数为23例,均为男性。年龄在15至30岁之间,平均年龄为18.25岁。所有患者均接受增强CT扫描。2例为I期肿瘤,9例为II期疾病,另外12例为III期肿瘤。20例患者采用外侧鼻切开术。1例肿瘤悬垂于口咽且蒂附着于鼻咽侧壁的患者经口途径切除,另1例局限于鼻咽和鼻后部的肿瘤患者经腭途径切除。1例肿瘤延伸至颞下窝的患者采用外侧鼻切开术加下唇下延伸术。11例患者在手术前48小时用明胶海绵进行术前栓塞。他们大多数为III期疾病,通过外侧鼻切开术进行手术治疗。大多数患者可采用外侧鼻切开术,切口可延长或不延长来切除肿瘤。