Pradhan G B N, Agrawal J
Department of Surgery, Nepal Medical College Teaching Hospital, Attarkhel, Jorpati, Kathmandu, Nepal.
Nepal Med Coll J. 2009 Sep;11(3):189-91.
The study was undertaken to see the infection rate of wound following emergency caesarean section with and without the use of topical fusidic acid. The study was carried out at Himal Hospital from April 2006 to Jan. 2008. A total of 70 child bearing patients who underwent emergency caesarean sections were included. All of the patients were given absorbable subcuticular stitches. Out of the 70 patients, 35 patients had topical fusidic acid immediately after subcuticular stitches followed by dry dressing. The other 35 patients had simple dressing with povidone- iodine. Six patients (17.1%) out of the 35 patients who had dressing with povidone-iodine developed wound infection at the surgical site and only 1 patient (2.8%) out of the 35 patients with fusidic acid developed wound infection. The use of fusidic acid reduced the infection rate by six times. The relation of fusidic acid to wound infection was statistically significant (p = 0.0460).
本研究旨在观察在紧急剖宫产术中使用和不使用局部用夫西地酸时伤口的感染率。该研究于2006年4月至2008年1月在喜马拉雅医院进行。共有70例接受紧急剖宫产的产妇纳入研究。所有患者均采用可吸收皮下缝线缝合。70例患者中，35例在皮下缝线后立即使用局部用夫西地酸，随后进行干性敷料包扎。另外35例患者采用聚维酮碘简单换药。在35例采用聚维酮碘换药的患者中，有6例（17.1%）手术部位发生伤口感染，而在35例使用夫西地酸的患者中，仅有1例（2.8%）发生伤口感染。夫西地酸的使用使感染率降低了6倍。夫西地酸与伤口感染的关系具有统计学意义（p = 0.0460）。
