Zhang Weiguo, Tong Qiang, Chen Zihua, Gao Yuanjun, Jin Shu, Wang Qiang, Li Shengbao
Department of Gastroenterology, Taihe Hospital, Yunyang Medical College, Shiyan, Hubei, China.
Scand J Gastroenterol. 2010 Sep;45(9):1093-6. doi: 10.3109/00365521003734182.
Gastric cancer can present as an exophytic lesion, diffuse infiltration of the gastric mucosa or even as a gastric ulcer, which can mimic a benign gastric ulcer. The purpose of this study was to evaluate the value of endoscopic ultrasound (EUS) in the differential diagnosis between benign and malignant gastric ulcer.
176 patients with gastric ulcer were divided into two groups on the basis of the cause of ulcer. Benign gastric ulcer group consisted of 102 patients and malignant gastric ulcer group consisted of 74 patients. All patients were examined by radial scanning echoendoscope (Olympus GF-UM 2000).
For diagnosis of malignant gastric ulcer, the sensitivity of EUS is 83.8%, the specificity is 62.7% and the accuracy is 71.6%.
The results demonstrate that EUS is a useful examination in differential diagnosis between benign and malignant gastric ulcer. However, it also has certain limitation which may be solved with more newer EUS applications and development.
胃癌可表现为外生性病变、胃黏膜弥漫性浸润,甚至表现为胃溃疡,后者可能酷似良性胃溃疡。本研究的目的是评估内镜超声(EUS)在鉴别良性和恶性胃溃疡中的价值。
176例胃溃疡患者根据溃疡病因分为两组。良性胃溃疡组102例,恶性胃溃疡组74例。所有患者均采用径向扫描超声内镜(奥林巴斯GF-UM 2000)进行检查。
对于恶性胃溃疡的诊断,EUS的敏感性为83.8%,特异性为62.7%,准确性为71.6%。
结果表明,EUS在鉴别良性和恶性胃溃疡方面是一种有用的检查方法。然而,它也有一定的局限性,随着更多更新的EUS应用和发展,这些局限性可能会得到解决。