Department of Infection, King's College London and St Thomas' Hospital, London, UK.
Lancet Infect Dis. 2010 Apr;10(4):227-39. doi: 10.1016/S1473-3099(10)70053-0.
Over the past decade, community-associated meticillin-resistant Staphylococcus aureus (MRSA) has emerged in patients without health-care contact, especially in the USA. Although data are limited, the prevalence of community-associated MRSA in Europe seems to be low but is increasing. The organism has been reported in most European countries, including The Netherlands and Nordic countries, which have low rates of health-care-associated MRSA. In Greece, rates of community-associated MRSA in some centres approach those of the USA. By contrast with North America, where the USA300 clone (ST8-IV) predominates, community-associated MRSA in Europe is characterised by clonal heterogeneity. The most common European strain is the European clone (ST80-IV), although reports of USA300 are increasing. Several community-associated MRSA clones have arisen in Europe, most notably the ST398-V pig-associated MRSA clone in The Netherlands and Denmark. An understanding of the epidemiology of community-associated MRSA is essential to guide new control initiatives to prevent these organisms from becoming endemic in Europe.
在过去十年中，无医疗接触史的社区相关性耐甲氧西林金黄色葡萄球菌（MRSA）在患者中出现，尤其多见于美国。尽管数据有限，但欧洲社区相关性 MRSA 的流行率似乎较低，但正在上升。该病原体已在包括荷兰和北欧国家在内的大多数欧洲国家中报告，这些国家的医疗保健相关性 MRSA 发生率较低。在希腊，一些中心的社区相关性 MRSA 发生率接近美国。与北美的情况不同，美国 300 克隆（ST8-IV）占主导地位，欧洲的社区相关性 MRSA 以克隆异质性为特征。最常见的欧洲菌株是欧洲克隆（ST80-IV），尽管美国 300 的报告正在增加。欧洲已经出现了几种社区相关性 MRSA 克隆，最著名的是荷兰和丹麦的与猪相关的 ST398-V 猪相关性 MRSA 克隆。了解社区相关性 MRSA 的流行病学对于指导新的控制措施以防止这些病原体在欧洲流行至关重要。
