Division of Infectious Diseases and Tropical Medicine, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Am J Med Sci. 2010 May;339(5):493-4. doi: 10.1097/MAJ.0b013e3181d94f90.
A pathological fracture is a break in a diseased bone caused by weakening of the bone structure by a pathological process with no identifiable trauma. Acute bacterial osteomyelitis that results in pathological fractures in the extremities is rare in adults. To our knowledge, we report the first case of Enterobacter aerogenes osteomyelitis of the right distal radius, complicated with a pathological fracture, in a 79-year-old man with diabetes, which was diagnosed by radiological, microbiological, and histopathological examinations. He recovered well after an 8-week course of antibiotics and surgical debridement. This highlights the fact that radial osteomyelitis should be included in the differential diagnosis when an elderly diabetic patient with no history of trauma presents with pain in the forearm.
病理性骨折是一种由病理过程引起的骨骼结构弱化导致的疾病性骨折，没有明确的创伤原因。急性细菌性骨髓炎导致四肢发生病理性骨折在成年人中较为罕见。据我们所知，我们报告了首例 79 岁糖尿病男性右侧桡骨远端继发于细菌感染的化脓性骨髓炎合并病理性骨折，通过影像学、微生物学和组织病理学检查进行诊断。他在接受 8 周的抗生素治疗和手术清创后恢复良好。这表明，当无创伤史的老年糖尿病患者出现前臂疼痛时，桡骨骨髓炎应纳入鉴别诊断。
