Division of Cardiology/Electrophysiology, Harper University Hospital, Wayne State University, Detroit, MI 48201, USA.
Am J Ther. 2011 Sep;18(5):350-4. doi: 10.1097/MJT.0b013e3181d539e6.
Although implantable cardioverter defibrillator (ICD) therapy is the standard of care for prevention of sudden cardiac death (SCD), its underutilization is a clinical concern. We performed a retrospective study on patients who underwent cardiac catheterization at a tertiary medical center to identify those who were eligible for ICD therapy as per the guidelines and those who actually received it as a part of treatment. Surprisingly, only 4.4% of eligible patients received ICD for SCD prevention. Assuming that the major cause of this underutilization of ICD therapy was low referral, we performed a structured survey among the referring physicians to assess specialists' availability, primary care physicians' role in ICD referral, patient management concerns, familiarity with ICD guidelines, and economics of ICD implantation. Physician response rate of the survey was 51% (35/68). Survey results showed that the common reasons for underreferral included nonavailability of electrophysiologists (34%), poor quality of life of patients (25.7%), patients not being on optimal therapy (25.7%), and low awareness (22.85%). Subsequently, a Monte Carlo simulation was used to assess a hypothetical survival of the study cohort, which showed that in an "ideal scenario" of ICD implantation, the mortality in the study cohort was decreased by 6.9% and 12.3% at 2- and 5-year follow-up, respectively. This study highlights the underutilization of ICDs and the referring physicians' approach to this therapy.
尽管植入式心脏复律除颤器 (ICD) 治疗是预防心脏性猝死 (SCD) 的标准治疗方法,但该治疗方法的应用不足是一个临床关注的问题。我们对在一家三级医疗中心进行心脏导管检查的患者进行了回顾性研究,以确定那些符合指南规定的 ICD 治疗适应证且实际接受该治疗的患者。令人惊讶的是,只有 4.4% 的符合条件的患者接受了 ICD 治疗以预防 SCD。假设 ICD 治疗应用不足的主要原因是转诊率低,我们对转诊医生进行了一项结构化调查,以评估专科医生的可及性、初级保健医生在 ICD 转诊中的作用、患者管理方面的担忧、对 ICD 指南的熟悉程度以及 ICD 植入的经济学。该调查的医生应答率为 51%(35/68)。调查结果显示,转诊不足的常见原因包括电生理学家资源不足(34%)、患者生活质量差(25.7%)、患者未接受最佳治疗(25.7%)以及意识不足(22.85%)。随后,我们使用蒙特卡罗模拟来评估研究队列的假设生存情况,结果表明,在 ICD 植入的“理想情况”下,研究队列的死亡率在 2 年和 5 年随访时分别降低了 6.9%和 12.3%。本研究强调了 ICD 的应用不足以及转诊医生对该治疗方法的态度。