Medical Research Foundation, Sankara Nethralaya, Chennai, Tamil Nadu, India.
Cornea. 2010 May;29(5):569-72. doi: 10.1097/ICO.0b013e3181bd9f2d.
To report a patient who developed bilateral corneal ectasia, during pregnancy, one and a half years after laser in situ keratomileusis for correction of myopia.
Case report with relevant literature review.
A 20-year-old woman, with a stable myopic astigmatism underwent laser in situ keratomileusis for the correction of her refractive error. Preoperative clinical examination and topographic automated keratoconus screening did not suggest keratoconus in either eye. The patient had a preoperative corneal thickness of 527 and 525 microm, and a postoperative residual bed thickness of 305 and 282 microm in the right and left eyes, respectively. After being fully satisfied with the outcome of the procedure, she reported 18 months later, in the first trimester of pregnancy, with signs and symptoms of corneal ectasia, which steadily worsened with advancing pregnancy.
Pregnancy could prompt hormonal changes, which in turn could affect the biomechanical stability of the cornea, leading to corneal ectasia.
报告 1 例患者在 LASIK 矫正近视 1 年半后，于孕期出现双眼角膜扩张。
病例报告并结合相关文献复习。
患者为 20 岁女性，稳定的近视散光，行 LASIK 矫正屈光不正。术前临床检查和角膜地形图自动筛查均未提示双眼存在圆锥角膜。右眼术前角膜厚度为 527μm，左眼为 525μm，术后右眼和左眼残余角膜床厚度分别为 305μm 和 282μm。患者对手术结果非常满意，18 个月后，即妊娠早期，出现角膜扩张的迹象和症状，随着妊娠的进展，病情逐渐加重。
妊娠可能导致激素变化，从而影响角膜的生物力学稳定性，导致角膜扩张。
