Kosinets V A, Sachek M G, Kondratenko G G
Khirurgiia (Mosk). 2010(1):59-63.
Randomized studies of combined treatment of 138 patients with toxic phase of general peritonitis were accomplished. We demonstrated a significant decrease in electric activity of the intestine and alteration of free-radical processes in patients with generalized purulent peritonitis. Administration of reamberin which contains succinic acid promoted restoration of the intestine's peristalsis to the 3rd day of postoperative period and effective correction of imbalance in free-radical processes system. Usage of reamberin in combined treatment of general peritonitis let lethality to be diminished from 16.49 to 9.76%.
对138例处于弥漫性腹膜炎中毒期的患者进行了联合治疗的随机研究。我们证明，弥漫性化脓性腹膜炎患者的肠道电活动显著降低，自由基过程发生改变。给予含有琥珀酸的雷美替胺可促进术后第3天肠道蠕动的恢复，并有效纠正自由基过程系统的失衡。在弥漫性腹膜炎的联合治疗中使用雷美替胺可使死亡率从16.49%降至9.76%。
